Changzhou University, China
👨🎓Profiles
🎓 Early Academic Pursuits
Zi-Qi Zhu embarked on his academic journey at Jiangsu Normal University, where he pursued a Bachelor of Science degree in Chemistry and Materials Science (2011-2015). His keen interest in organic synthesis led him to continue his education at the same institution, earning a Master of Science degree (2015-2018) under the guidance of Prof. Feng Shi. His master's research laid a strong foundation in chemical methodologies, sparking his interest in transition metal catalysis and asymmetric synthesis. He later pursued a Ph.D. at Nanjing University (2018-2022) under the supervision of Prof. Zhuangzhi Shi, focusing on cutting-edge developments in catalytic transformations.
🏛️ Professional Endeavors
Following the completion of his doctorate, Dr. Zhu joined the School of Petrochemical Engineering at Changzhou University in 2022 as a Lecturer. His rapid contributions and research advancements led to his promotion as an Associate Professor in 2023. Working closely with Prof. Feng Shi’s research group, he has played a pivotal role in advancing the field of organocatalysis and chiral heterocyclic chemistry.
🔬 Contributions and Research Focus
Dr. Zhu’s research primarily revolves around transition metal-catalyzed cross-couplings and organocatalyzed cyclizations, with a particular emphasis on asymmetric organocatalysis and axial chirality chemistry. His work has significantly contributed to the synthesis and development of chiral drugs, which hold great potential in pharmaceutical applications. By exploring novel catalytic methodologies, his research enhances efficiency and selectivity in chiral compound synthesis, making a substantial impact in organic chemistry and medicinal research.
🌍 Impact and Influence
With over 15 high-impact publications in peer-reviewed international journals, Dr. Zhu’s research has gained significant recognition in the field of synthetic chemistry. His contributions to asymmetric catalysis and chiral drug synthesis have influenced both academic research and industrial applications. His studies on chiral heterocycles provide valuable insights for drug design and development, with implications in creating more effective pharmaceutical compounds.
📖 Academic Grants and Leadership
Dr. Zhu has demonstrated strong leadership in securing research funding. He successfully chaired the National Natural Science Foundation of China (2024) and the Natural Science Foundation of Jiangsu Province (2023). These grants have allowed him to expand his research group and explore new frontiers in chiral chemistry, reinforcing his reputation as a rising scholar in the field.
📚 Teaching Experience and Mentorship
As an Associate Professor, Dr. Zhu actively engages in teaching undergraduate and postgraduate students in petrochemical engineering and organic chemistry. He is dedicated to mentoring young researchers, guiding them in advanced synthetic methodologies and catalysis. His mentorship has helped shape future scientists, fostering an environment of innovation and scientific rigor.
🏆 Technical Skills and Expertise
Dr. Zhu possesses extensive expertise in asymmetric synthesis, transition metal catalysis, and organocatalysis. His technical proficiency includes:
- Catalytic asymmetric synthesis for chiral drug development
- Transition metal-catalyzed reactions for novel heterocyclic compounds
- Spectroscopic techniques (NMR, IR, MS, X-ray Crystallography) for structural characterization
- Computational chemistry tools for reaction mechanism elucidation
🚀 Legacy and Future Contributions
With a strong foundation in synthetic organic chemistry, Dr. Zhu’s future work aims to develop novel catalytic strategies for sustainable and highly efficient asymmetric transformations. His ongoing research in axial chirality chemistry is expected to pave the way for innovative applications in material science and pharmaceuticals. By continuously expanding the frontiers of organocatalysis, he aspires to leave a lasting impact on chemical synthesis and drug discovery.
📖Notable Publications
Nickel‐Catalyzed Intermolecular Asymmetric Addition of Aryl Iodides across Aldehydes
Authors: Ziqi Zhu, Jieshuai Xiao, Mingjie Li, Zhuangzhi Shi
Journal: Angewandte Chemie International Edition
Year: 2022
Nickel‐Catalyzed Stereo‐ and Enantioselective Cross‐Coupling of gem‐Difluoroalkenes with Carbon Electrophiles by C−F Bond Activation
Authors: Ziqi Zhu, Lin Lin, Jieshuai Xiao, Zhuangzhi Shi
Journal: Angewandte Chemie International Edition
Year: 2022
Regioselective [3+3] Cyclization of 2‐Indolymethanols with Vinylcyclopropanes via Metal Catalysis
Authors: Zi‐Qi Zhu, Lei Yu, Meng Sun, Guang‐Jian Mei, Feng Shi
Journal: Advanced Synthesis & Catalysis
Year: 2018
Diastereo- and enantioselective construction of biologically important pyrrolo[1,2-a]indole scaffolds via catalytic asymmetric [3 + 2] cyclodimerizations of 3-alkyl-2-vinylindoles
Authors: Zi-Qi Zhu, Lei Yin, Yang Wang, Yang Shen, Can Li, Guang-Jian Mei, Feng Shi
Journal: Organic Chemistry Frontiers
Year: 2017
Enantioselective Direct α-Arylation of Pyrazol-5-ones with 2-Indolylmethanols via Organo-Metal Cooperative Catalysis
Authors: Zi-Qi Zhu, Yang Shen, Jin-Xi Liu, Ji-Yu Tao, Feng Shi
Journal: Organic Letters
Year: 2017
Catalytic Asymmetric [3+2] Cycloadditions of C‐3 Unsubstituted 2‐Indolylmethanols: Regio‐, Diastereo‐ and Enantioselective Construction of the Cyclopenta[b]indole Framework
Authors: Zi‐Qi Zhu, Yang Shen, Xiao‐Xue Sun, Ji‐Yu Tao, Jin‐Xi Liu, Feng Shi
Journal: Advanced Synthesis & Catalysis
Year: 2016