Tabriz University of Medical Sciences | Iran
Dr. Abolfazl Akbarzadeh, a distinguished Associate Professor of Medicinal Chemistry (Nanobiomedicine) at the Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Iran, is internationally recognized as a Highly Cited Researcher by Thomson Reuters ISI Web of Science, highlighting his placement among the top 1% of scholars worldwide in citations. With an H-index of 66 (Scopus) and over 21,700 citations from 18,576 documents, Dr. Akbarzadeh has made profound contributions to nanomedicine, drug delivery, and tissue engineering, with more than 280 ISI-indexed publications. His pioneering work focuses on the design, synthesis, and characterization of functionalized nanoparticles and nanostructures for biomedical applications, particularly in controlled delivery of anticancer agents, including doxorubicin-loaded Fe₃O₄ magnetic nanoparticles and polymer-coated smart nanocarriers. These innovative systems enhance therapeutic efficacy while minimizing systemic toxicity and enable targeted delivery to cancerous tissues. In addition to drug delivery, Dr. Akbarzadeh has significantly advanced nanobiomaterials for regenerative medicine, including engineering hydrogels with tunable mechanical properties for soft tissue regeneration and the development of polymeric micro- and nanoparticles containing proteins, peptides, and anticancer drugs. He has applied his expertise in 3D bioprinting, stem cell therapy, and nanofiber design for skin and bone tissue regeneration, exploring natural and biocompatible materials such as propolis and zeolite/hydroxyapatite nanoparticles to promote rapid tissue repair. His work integrates microfluidics for precision synthesis of nanobiomaterials, providing platforms for efficient nanobio-targeting and biomedical engineering applications. Dr. Akbarzadeh’s interdisciplinary research encompasses organic, inorganic, analytical chemistry, nanotechnology, and bioengineering, reflecting his robust academic foundation from B.Sc. in Applied Chemistry, M.Sc. in Pure Chemistry, to a Ph.D. in Medicinal Chemistry. His international experience as a visiting professor at Northeastern University (Boston, USA) and UCLA (California, USA) underscores his global scientific influence. Beyond research, he has mentored numerous students in nanobiomedicine and nanotechnology. His innovations have resulted in multiple patents for nanoparticle-based drug delivery systems earning him numerous national awards and recognition for excellence in scientific research and innovation, affirming his status as a leading figure in nanobiomedicine and translational biomedical science.
Featured Publications
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Jafari-Najaf-Abadi, A., Pazoki-Toroudi, H., Hadjianfar, M., Mirjafary, Z., … (2025). Core–shell nanofibers for localized melanoma therapy delivering Pioglitazone nanoemulsions and gemcitabine dual loaded system. Scientific Reports, 15(1), 28401.
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Haghighi, M. A., Jahandideh, A., Chamheidari, G. A., Hesaraki, S., Akbarzadeh, A. (2025). Therapeutic potential of nanofibrous scaffolds in calvarial bone regeneration. BioNanoScience, 15(3), 386.
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Fesendouz, S. A., Hamishehkar, H., Alizadeh, E., Rahbarghazi, R., … (2025). Bactericidal activity and biofilm eradication of Pseudomonas aeruginosa by liposome-encapsulated piperacillin/tazobactam. BioNanoScience, 15(1), 87.
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Hajati Ziabari, A., Jahandideh, A., Akbarzadeh, A., Mortazavi, P. (2025). Evaluation of the effects of curcumin/polycaprolactone nano composite on the healing of experimental osteomyelitis in rabbit tibia. Iranian Journal of Veterinary Surgery, 20(1), 38–46.
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Hajishoreh, N. K., Mellatyar, H., Kaamyabi, S., Abasalizadeh, F., Akbarzadeh, A. (2024). Preparation and evaluation of polyurethane-based nanofibers for controlled release of simvastatin for the treatment of cardiac disorders. BioNanoScience, 14(2), 1687–1695.