Yi Yan Yang | Nanomedicine | Best Researcher Award -1584

Prof. Dr. Yi Yan Yang | Nanomedicine | Best Researcher Award

Bioprocessing Technology Institute, Singapore

๐Ÿ‘จโ€๐ŸŽ“Profiles

๐ŸŽ“ Early Academic Pursuits

Yi Yan Yang began her academic journey in chemical engineering at Tsinghua University, P.R. China, where she served as an Assistant/Associate Professor from 1990 to 1998. Her foundation in polymer science and chemical engineering laid the groundwork for a remarkable career in biomedical innovation and nanomedicine. This period marked her transition into interdisciplinary research, focusing on advanced materials and their practical applications.

๐Ÿ’ผ Professional Endeavors

Her illustrious career spans multiple leadership roles within ASTAR, Singapore. She served as Group Leader at the Institute of Bioengineering and Nanotechnology (IBN), progressing to key executive positions such as Covering Executive Director at both IBN and the Institute of Bioengineering and Bioimaging. Currently, she holds the title of Distinguished Principal Scientist at the Bioprocessing Technology Institute (BTI), ASTAR. Additionally, since 2019, she has been an Adjunct Professor at the Department of Orthopedics, National University of Singapore (NUS). Her leadership and strategic vision have significantly shaped Singapore's research landscape.

๐Ÿ“š Contributions and Research Focus

She has made groundbreaking contributions in the fields of polymer science, nanocarriers, nanomedicine, and drug delivery systems. She has led 56 research projects, collaborating with global industry leaders like IBM, Merck MSD, and Procter & Gamble. Her work includes the development of antimicrobial and antiviral polymer coatings, polymeric hydrogels for antibody delivery, and novel nanocarriers for mRNA vaccine delivery.ย Her innovations extend to tackling antimicrobial resistance, polymer-based drug delivery systems, and mRNA therapeutics, significantly contributing to infectious disease treatment and next-generation vaccines.

๐Ÿ”ญ Impact and Influence

Her research has had a global impact, as evidenced by her h-index of 95 and over 29,000 citations on Google Scholar. Recognized as a Clarivate Highly Cited Researcher in 2022, her contributions include pioneering antimicrobial polymers, which were named among Scientific Americanโ€™s Top 10 World-Changing Ideas. Her technologies have led to the founding of companies like TriSafe HealthTech Pte. Ltd., translating laboratory research into real-world applications that address critical global health challenges.

๐ŸŒŸ Academic Publications and Patents

She has authored 303 publications in prestigious journals, including Nature Materials, Nature Nanotechnology, ACS Nano, and Advanced Materials. Her portfolio also boasts 92 patents, demonstrating her innovative spirit and commitment to advancing technology. These publications and patents underscore her expertise in drug/gene delivery systems, antimicrobial technologies, and nanomedicine.

๐Ÿ’ก Collaborations and Partnerships

Her collaborations with globally renowned researchers, such as Dr. James L. Hedrick (IBM Almaden Research Center) and Dr. Yue Wan (Genome Institute of Singapore), have led to advancements in polymer chemistry, mRNA vaccine development, and therapeutics. Her partnerships extend to prominent institutions and industries, including Smithfield Hog Production, IHI, and ST Dynamics, fostering innovation across biomedical, pharmaceutical, and consumer care sectors.

๐Ÿ“ˆ Legacy and Future Contributions

Her legacy is defined by her transformative work in biomedicine, polymer science, and infectious disease control. Her technologies have not only influenced the academic community but have also resulted in practical solutions addressing global health crises. Looking ahead, Dr. Yang remains committed to advancing mRNA nanoformulation, antimicrobial therapies, and nanocarrier systems to revolutionize healthcare delivery.

๐Ÿ’ฅ Technical Skills and Expertise

She is a pioneer in the synthesis and characterization of functional polymers, lipid nanoparticles, and self-assembling macromolecules. Her expertise in nanomedicine and drug delivery is complemented by her skills in developing mRNA nanoformulations, antimicrobial polymers, and polymeric hydrogels for various biomedical applications.

๐Ÿ‘จโ€๐ŸŽ“ Teaching Experience and Mentorship

As an Adjunct Professor at NUS, She has actively engaged in mentoring students and early-career researchers, fostering the next generation of scientists. Her leadership roles in research institutes and collaborative projects reflect her dedication to knowledge sharing and academic development.

๐Ÿ› ๏ธ Consultancy and Industry Impact

Her collaborations with industry giants, including IBM, Procter & Gamble, and Merck MSD, have translated scientific innovations into commercial products. These partnerships have led to the development of groundbreaking solutions such as antimicrobial coatings, polymeric hydrogels, and nanocarriers for drug and vaccine delivery, contributing to advancements in healthcare, agriculture, and consumer care.

๐Ÿ“–Notable Publications

  1. Durable cross-protective neutralizing antibody responses elicited by lipid nanoparticle-formulated SARS-CoV-2 mRNA vaccines
    • Authors: Bae, K.H., Shunmuganathan, B., Zhang, L., White, K.P., Yang, Y.Y.
    • Journal: npj Vaccines
    • Year: 2024
  2. A multiantigenic antibacterial nanovaccine utilizing hybrid membrane vesicles for combating Pseudomonas aeruginosa infections
    • Authors: Peng, X., Luo, Y., Yang, L., Tian, G.-B., Ding, X.
    • Journal: Journal of Extracellular Vesicles
    • Year: 2024
  3. Polymeric micellar nanoparticles for effective CRISPR/Cas9 genome editing in cancer
    • Authors: Li, Y., Li, C., Yan, J., Yang, Y.Y., Yuan, P.
    • Journal: Biomaterials
    • Year: 2024
  4. Quantitative analysis of mRNA-lipid nanoparticle stability in human plasma and serum by size-exclusion chromatography coupled with dual-angle light scattering
    • Authors: Liau, B., Zhang, L., Ang, M.J.Y., Bae, K.H., Yang, Y.Y.
    • Journal: Nanomedicine: Nanotechnology, Biology, and Medicine
    • Year: 2024
  5. Biofunctional lipid nanoparticles for precision treatment and prophylaxis of bacterial infections
    • Authors: Peng, X., Chen, J., Gan, Y., Yuan, P., Ding, X.
    • Journal: Science Advances
    • Year: 2024

 

Shaoqing Zhu | Pharmaceutical Analysis | Best Researcher Award -1443

Mr. Shaoqing Zhu | Pharmaceutical Analysis | Best Researcher Award

Zhenjiang College, China

๐Ÿ‘จโ€๐ŸŽ“Profile

๐ŸŽ“ Early Academic Pursuits

Shaoqing Zhu completed a Bachelor's Degree in Traditional Chinese Medicine (TCM) at Nanjing University of Chinese Medicine in 2014. Building upon this foundation, He pursued and achieved a Doctorate in TCM at the same institution in 2020, establishing a strong base in traditional Chinese medicinal practices.

๐Ÿ’ผ Professional Endeavors

Currently a Lecturer and Director at the Zhenjiang Key Laboratory of Functional Chemistry at Zhenjiang College, His professional role includes responsibilities in education, research, and laboratory leadership. Notably, He was selected for the "169 Project" for young academic and technical talents in Zhenjiang City, along with recognition in the Young Scientific and Technological Talent Support Project, underscoring His influence and potential in the scientific field.

๐Ÿ”ฌ Contributions and Research Focus

His research spans post-harvest processing and preparation of TCM, uncovering pharmacological foundations, and finding resourceful applications for byproducts from agricultural processes. Notably, Shaoqing has led projects funded by the Natural Science Foundation of Jiangsu Higher Education Institutions, Science and Technology Planning Projects of Zhenjiang City, and other significant research initiatives, advancing methods for medicinal material processing and quality control.

๐ŸŒ Impact and Influence

Through research on drying and processing methods for medicinal materials, Shaoqing has set benchmarks in standardization and quality control within TCM, directly influencing industrial practices. Shaoqingโ€™s efforts have led to industry advancements, particularly in pharmaceutical development and the application of sustainable processing techniques.

๐Ÿ“Š Academic Cites

With 13 SCI-indexed publications, Shaoqingโ€™s work has achieved an H-index of 10 and has been cited 322 times, reflecting a strong academic presence and relevance. These publications cover influential studies in post-harvest medicinal preparation, resource utilization, and processing optimization.

๐Ÿ›  Technical Skills

He has expertise in UPLC-MS/MS (Ultra Performance Liquid Chromatography coupled with Tandem Mass Spectrometry), and specializes in optimizing TCM processing techniques. He is proficient in designing and leading complex research projects that align with industry standards and is adept at translating research findings into actionable industrial improvements.

๐Ÿ‘ฉโ€๐Ÿซ Teaching Experience

As a Lecturer, Shaoqing provides instruction and mentorship within the School of Pharmaceutical & Chemical Technology at Zhenjiang College. His teaching incorporates hands-on research experience, giving students a practical view of TCMโ€™s pharmaceutical applications and post-harvest processing.

๐Ÿ† Legacy and Future Contributions

His work in TCM processing and pharmacology is laying the groundwork for future innovations in sustainable medicine production. With ongoing projects and collaborations, he aims to refine medicinal standards and elevate the scientific basis of TCM. Future contributions will likely expand Shaoqing's influence in TCM standardization and green processing practices, impacting both academic and industrial sectors.

๐Ÿ“–Notable Publications

"Microbiota, metabolites and mucosal immunity as potential targets of traditional Chinese medicine for respiratory diseases based on the lung-gut crosstalk"
Authors: Wang, W., Zhu, S., Zhang, Y., Yang, H., Wu, H.
Journal: Pharmacological Research - Modern Chinese Medicine
Year: 2024

"Authentication of Asini Corii Colla and Taurus Corii Colla based on UPLC-MS/MS and the discovery of antioxidant peptides associated with the PI3K-AKT pathway"
Authors: Wang, W., Chu, L., Chen, L., Zhang, Y., Yang, H.
Journal: Natural Product Research
Year: 2023

"Multi-constituents variation in medicinal crops processing: Investigation of nine cycles of steam-sun drying as the processing method for the rhizome of Polygonatum cyrtonema"
Authors: Zhu, S., Liu, P., Wu, W., Wang, W., Duan, J.-A.
Journal: Journal of Pharmaceutical and Biomedical Analysis
Year: 2022

"Study on modern drying processing method for Trichosanthis Pericarpium based on multi-bioactive constituents"
Authors: Zhang, H.-Q., Liu, P., Qian, D.-W., Li, H.-W., Duan, J.-A.
Journal: Chinese Traditional and Herbal Drugs
Year: 2020

"Comparative analysis of nucleosides, nucleobases, and amino acids in different parts of Angelicae Sinensis Radix by ultra high performance liquid chromatography coupled to triple quadrupole tandem mass spectrometry"
Authors: Qu, C., Yan, H., Zhu, S.-Q., Qian, D.-W., Duan, J.-A.
Journal: Journal of Separation Science
Year: 2019

"Modelling of the Moisture Dynamic Process and Effects on Multiple Functional Components of Gardenia jasminoides Ellis with Different Drying Methods"

Authors: Wang, X.-H., Zhu, S.-Q., Gu, W., Zhou, C., Wang, F.
Journal: Science and Technology of Food Industry
Year: 2019

"Drying processing method for Zingiberis Rhizoma based on multiple bioactive constituents"

Authors: Li, P.-H., Wu, Q.-N., Yan, H., Huang, S.-L., Wang, G.-Q.
Journal: Chinese Traditional and Herbal Drugs
Year: 2018