Professor | Henan Normal University | China
Professor Zhang Hua is a distinguished scholar in the fields of functional dye molecular engineering, biosensing, and advanced fluorescence technologies. With a Ph.D. from Dalian University of Technology, she has established a strong scientific presence through innovative research that bridges chemistry, materials science, and biomedicine. As a recipient of the National Excellent Young Scientist Fund and a recognized Henan Province Expert, Professor Zhang leads a university-level scientific innovation team focused on developing high-performance fluorescent dyes and imaging tools for disease diagnosis and molecular detection. Her research has significantly advanced the design and functional tuning of organic dyes for two-photon fluorescence applications, enabling highly sensitive and specific detection of key biomolecules such as nucleic acids, enzymes, and proteins. These technologies have been successfully applied to single-cell analysis, high-resolution bioimaging, and early-stage diagnostics. Professor Zhang has also driven the development of dye-based technologies that support industrial product validation, exemplified by contributions that helped a commercial product meet stringent EU REACH certification standards. Her growing portfolio of nine granted Chinese invention patents and 78 SCI-indexed publications, supported by an H-index of 27 and more than 2,669 citations, reflects her significant scholarly influence. She has completed multiple projects funded by the National Natural Science Foundation of China and is actively engaged in ongoing national-level research. Her memberships in key professional committees highlight her leadership in China’s analytical chemistry and biosensing communities. Professor Zhang’s work continues to accelerate innovation at the chemistry–biology interface, driving forward technologies that impact both scientific research and real-world biomedical applications.
Featured Publications
Yang, Y. T., Liu, Y., …, & Zhang, H. (2025). H2S-activated Type-I photochemical probe: Fluorescent self-reporting for real-time monitoring of tumor ablation. Analytical Chemistry, 97(42), 23467–23476.
Han, J. N., Yang, M., …, & Zhang, H. (2025). Light-driven ESIPT-based anthraquinone analogues for synergistic fluorescent self-reporting and photodynamic therapy of malignant tumors. Journal of Medicinal Chemistry, 68(19), 20814–20826.
Liu, J., Liu, Y., Zhi, S., Yang, Y., Kim, H., Wu, D., Wang, G., James, T. D., Yoon, J., & Zhang, H. (2025). A nanotherapeutic agent for synergistic tumor therapy: Co-activation of photochemical-biological effects. Angewandte Chemie International Edition.
Niu, H. Y., Wang, S. N., …, & Zhang, H. (2025). Naphthalimide-based Type-I nano-photosensitizers for enhanced antitumor photodynamic therapy: H₂S synergistically regulates PeT and self-assembly. Angewandte Chemie International Edition. (Early Access).
Lv, C., Li, Z., Liu, W., Yang, M., Zhang, H., Fan, J., & Peng, X. (2025). An activatable chemiluminescent self-reporting sulfur dioxide donor for inflammatory response and regulation of gaseous vasodilation. ACS Sensors.