Kaiyin Yang | Molecular Biology | Research Excellence Award

Dr. Kaiyin Yang | Molecular Biology | Research Excellence Award

North China University of Science and Technology | China

Dr. Kaiyin Yang is a pharmacologist with a Doctor of Medicine degree, specializing in protein structure-based drug discovery and small-molecule targeted protein degradation. His research focuses on the rational design, synthesis, and mechanistic evaluation of novel anticancer agents, particularly PROTACs and enzyme-targeting small molecules. As Principal Investigator of a Hebei Provincial Youth Science Fund project, he is developing innovative HK2-targeting degraders for colon cancer therapy. His work also includes kinase inhibitors, metabolic enzyme modulation, and natural product-derived anticancer compounds. Dr. Yang’s studies integrate medicinal chemistry, chemical biology, and pharmacological approaches to advance precision oncology and targeted cancer therapeutics.

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Vijaya Sarangthem | Biochemistry | Best Researcher Award

Dr. Vijaya Sarangthem | Biochemistry | Best Researcher Award

Research Professor | Kyungpook National University | South Korea

Dr. Sarangthem Vijaya Devi is an innovative biomedical scientist with over twelve years of expertise in biopolymer-based drug delivery, regenerative medicine, and nanotechnology, focusing on the design and development of elastin-like polypeptide (ELP)–based biomaterials for targeted therapeutics. Her doctoral research at Kyungpook National University, South Korea, involved constructing IL-4 receptor–targeting ELP systems for precise drug delivery, laying the foundation for her pioneering work in tumor-targeted cancer therapy and gene delivery. As a postdoctoral fellow, she led the development of multivalent ELP nanoparticles and depot systems, optimizing pharmacokinetics and tissue biodistribution, and establishing platforms for enhanced therapeutic efficacy. At AIIMS, New Delhi, Dr. Vijaya Devi advanced regenerative medicine applications by developing self-assembling ELP hydrogels and 3D scaffolds for mesenchymal stem cell culture, differentiation, and tissue regeneration. She further integrated 3D bioprinting technologies to create artificial tissue models for high-throughput drug screening and preclinical evaluation. Her ongoing work as a visiting research professor at Kyungpook National University focuses on ELP-driven 3D culture platforms, enabling scalable and reproducible organoid and spheroid models for precision medicine. Dr. Vijaya Devi’s research portfolio includes over 16 high-impact publications, several as corresponding or first author, highlighting her contributions to nanoparticle engineering, biomaterial optimization, and translational therapeutics. She has contributed to patents on ELP-based hydrogels for tissue regeneration and nanocarriers for oncology drug delivery, demonstrating the translational potential of her work. Recognized with multiple awards, including the Best Article Award and DST Fellowship, her research bridges fundamental science with industry applications, emphasizing scalability, regulatory compliance, and interdisciplinary collaboration. Her expertise encompasses gene delivery systems, molecular imaging, biomaterials engineering, and organoid culture, making her a leading researcher in precision therapeutics. Dr. Vijaya Devi continues to drive innovations in ELP biomaterials for cancer therapy, tissue engineering, and high-throughput drug discovery, positioning her as a global leader in biomedical research and translational medicine.

Profiles : Scopus | ORCID | Google Scholar | Research Gate

Featured Publications

  • Lee, Y.-J., Hong, J., Seo, B.-Y., Lee, B.-H., Sarangthem, V.*, & Park, R.-W. (2025). Strategic optimization of nanoparticle characteristics to enhance tumor targeting and doxorubicin delivery. International Journal of Nanomedicine, 20, 6357–6378.

  • Hong, J., Sim, D., Lee, B.-H., Sarangthem, V.*, & Park, R.-W. (2024). Multifunctional elastin-like polypeptide nanocarriers for efficient miRNA delivery in cancer therapy. Journal of Nanobiotechnology, 22(1), 293.

  • Sarangthem, V., Sharma, H., Mendiratta, M., Sahoo, R. K., Park, R.-W., Kumar, L., Singh, T. D., & Mohanty, S. (2022). Application of bio-active elastin-like polypeptide on regulation of human mesenchymal stem cell behavior. Biomedicines, 10(5), 1151.

  • Sarangthem, V.*, Sharma, H., Goel, R., Ghose, S., Park, R.-W., Mohanty, S., Chaudhuri, T. K., Dinda, A. K., & Singh, T. D. (2022). Application of elastin-like polypeptide (ELP) containing extracellular matrix (ECM) binding ligands in regenerative medicine. International Journal of Biological Macromolecules.

  • Sarangthem, V., Yi, A., Kim, Y., Rehemtulla, A., Lee, B.-H., Jeon, Y. H., Singh, T. D., & Park, R.-W. (2021). Therapeutic effect of IL4 receptor targeting pro-apoptotic peptide (AP1-ELP-KLAK) in glioblastoma tumor model. International Journal of Nanomedicine, 16, 5039–5052.

 

Şengül Alpay Karaoğlu | Molecular Biology | Women Researcher Award

Prof Dr. Şengül Alpay Karaoğlu | Molecular Biology | Women Researcher Award

Recep Tayyip Erdoğan University, Turkey

 Profiles👨‍🎓

 Early Academic Pursuits🎓

Prof. Dr. Sengul Alpay Karaoglu's academic foundation is grounded in Microbial Physiology, earning her MSc in 2015-2016 from Recep Tayyip Erdoğan University. Her early focus included critical areas such as General Microbiology, Virology, Immunology, and Molecular Biology and Genetics. Over time, she has expanded her expertise into Biotechnology, Biodiversity Conservation, Pharmacology, and Mycology. Her solid academic background laid the groundwork for her substantial contributions in microbial and environmental sciences.

 Professional Endeavors💼

She has held multiple influential academic roles at Recep Tayyip Erdoğan University, including Faculty Board Member (2015–2022) and Head of the Biology Department (2016–present). She was also appointed Professor at Gümüşhane University in 2022. Her academic career spans two decades of service, where she has actively contributed to curriculum development and academic leadership in Biology, Microbiology, and Mycology. Beyond administrative roles, she is a patent holder and has led numerous research projects, showcasing her multidisciplinary talents in both teaching and research.

 Contributions and Research Focus🔬

Her research portfolio is rich with innovative work across microbiology, pharmacology, and biotechnology. Her research has notably contributed to understanding antimicrobial drugs and microbial biodiversity. Major highlights include: Antimicrobial properties of lactic acid bacteria isolated from honeybees (Apis mellifera), Characterization of Bacillus species and their bioactive metabolites, including antifungal and antibacterial activities, Studies on antibiotic resistance in Escherichia coli strains and molecular identification of Trichoderma species for biological control.

Her research contributions are reflected in several peer-reviewed publications and patents, such as her invention on an anti-helicobacter effective azo dye and urease enzyme inhibitor. Her work on synthesizing Penicillin-, Cephalosporin-, and Norfloxacin-Azole hybrid molecules demonstrates her role in advancing antimicrobial drug design.

 Impact and Influence🌍

Her impact on the scientific community is wide-reaching, particularly in microbiology and biotechnology. Her TÜBİTAK projects and work with higher education institutions underscore her leadership in addressing critical environmental and agricultural challenges. The innovative nature of her research has implications for antimicrobial therapies, environmental microbiology, and pharmacology, helping shape global understanding in these fields.

 Academic Cites and Recognition📚

Her research output has been widely cited in scientific journals and conferences, contributing to her reputation as a leading academic in Turkey and beyond. Her studies have enhanced the scientific understanding of antibiotic resistance and biological control mechanisms.

Technical Skills🛠️

Prof. Karaoglu’s technical expertise spans advanced microbiological techniques, including microbial culturing, genetic sequencing, molecular biology assays, and biotechnological applications. Her ability to blend laboratory research with real-world environmental applications is a hallmark of her technical acumen.

Teaching Experience👩‍🏫

She has an extensive teaching career, offering courses across several key fields, including: Molecular Cell Biology, Environmental Biotechnology, Food Microbiology, Virology. Antimicrobial Drugs and Their Mechanisms of Action Her commitment to academic excellence is demonstrated through her management of multiple graduate theses, mentoring students in cutting-edge microbiological research.

Legacy and Future Contributions🏆

Her legacy is one of scientific innovation and educational leadership. As a professor and researcher, she has not only contributed to critical advancements in microbiology and pharmacology but also nurtured the next generation of scientists. Moving forward, her work in biotechnology, antimicrobial resistance, and environmental microbiology will continue to be pivotal in addressing global scientific challenges. Prof. Karaoglu’s extensive portfolio ensures her lasting influence on both academia and the scientific community.

Notable Publications📖

"Characterization of chitin and description of its antimicrobial properties obtained from Cydalima perspectalis adults"

Authors: Kılcı, L., Altun, N., Karaoğlu, Ş.A., Karaduman Yeşildal, T.

JournalPolymer Bulletin

Year: 2024

"Prevalence and Phylogenetic Network Analysis of Nosema apis and Nosema ceranae Isolates from Honeybee Colonies in Türkiye"

Authors: Akpınar, R.K., Gürler, A.T., Bölükbaş, C.S., Küçükoğlu, B., Kurt, M.

JournalActa Parasitologica

Year: 2024

"Prevalence and molecular analysis of some important viruses in honey bee colonies in Türkiye: the status of multiple infections"

Authors: Akpinar, R., Ozan, E., Celik, S., Yaldiz, M., Karaoglu, S.A.

JournalArchives of Virology

Year: 2024

"Synthesis, Antimicrobial Activities, and Molecular Modeling Studies of Agents for the Sortase A Enzyme"

Authors: Tatar Yilmaz, G., Yayli, N., Tüzüner, T., Bozdeveci, A., Alpay Karaoğlu, Ş.

JournalChemistry and Biodiversity

Year: 2024

"Determination of plant growth promoting properties and bioremediation potentials of Bacillus mycoides Flügge and B. thuringiensis Berliner"

Authors: Üreyen Esertaş, Ü.Z., Bozdeveci, A., Uzunalioğlu, E., Alpay Karaoğlu, Ş.

JournalTrakya University Journal of Natural Sciences

Year: 2024

"Some Schiff Bases Containing Eugenol and Guaiacol: Comparison of Urease Inhibition and Anti-Helicobacter pylori Activities with Its Azo Analogs"

Authors: Kantar, C., Baltaş, N., Karaoğlu, Ş.A., Şaşmaz, S.

JournalPharmaceutical Chemistry Journal

Year: 2024