Abolfazl Akbarzadeh | Nanotechnology | Best Researcher Award

Prof. Abolfazl Akbarzadeh | Nanotechnology | Best Researcher Award

Tabriz University of Medical Sciences | Iran

Dr. Abolfazl Akbarzadeh, a distinguished Associate Professor of Medicinal Chemistry (Nanobiomedicine) at the Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Iran, is internationally recognized as a Highly Cited Researcher by Thomson Reuters ISI Web of Science, highlighting his placement among the top 1% of scholars worldwide in citations. With an H-index of 66 (Scopus) and over 21,700 citations from 18,576 documents, Dr. Akbarzadeh has made profound contributions to nanomedicine, drug delivery, and tissue engineering, with more than 280 ISI-indexed publications. His pioneering work focuses on the design, synthesis, and characterization of functionalized nanoparticles and nanostructures for biomedical applications, particularly in controlled delivery of anticancer agents, including doxorubicin-loaded Fe₃O₄ magnetic nanoparticles and polymer-coated smart nanocarriers. These innovative systems enhance therapeutic efficacy while minimizing systemic toxicity and enable targeted delivery to cancerous tissues. In addition to drug delivery, Dr. Akbarzadeh has significantly advanced nanobiomaterials for regenerative medicine, including engineering hydrogels with tunable mechanical properties for soft tissue regeneration and the development of polymeric micro- and nanoparticles containing proteins, peptides, and anticancer drugs. He has applied his expertise in 3D bioprinting, stem cell therapy, and nanofiber design for skin and bone tissue regeneration, exploring natural and biocompatible materials such as propolis and zeolite/hydroxyapatite nanoparticles to promote rapid tissue repair. His work integrates microfluidics for precision synthesis of nanobiomaterials, providing platforms for efficient nanobio-targeting and biomedical engineering applications. Dr. Akbarzadeh’s interdisciplinary research encompasses organic, inorganic, analytical chemistry, nanotechnology, and bioengineering, reflecting his robust academic foundation from B.Sc. in Applied Chemistry, M.Sc. in Pure Chemistry, to a Ph.D. in Medicinal Chemistry. His international experience as a visiting professor at Northeastern University (Boston, USA) and UCLA (California, USA) underscores his global scientific influence. Beyond research, he has mentored numerous students in nanobiomedicine and nanotechnology. His innovations have resulted in multiple patents for nanoparticle-based drug delivery systems earning him numerous national awards and recognition for excellence in scientific research and innovation, affirming his status as a leading figure in nanobiomedicine and translational biomedical science.

Profiles : Scopus | ORCID | Google Scholar

Featured Publications

  • Jafari-Najaf-Abadi, A., Pazoki-Toroudi, H., Hadjianfar, M., Mirjafary, Z., … (2025). Core–shell nanofibers for localized melanoma therapy delivering Pioglitazone nanoemulsions and gemcitabine dual loaded system. Scientific Reports, 15(1), 28401.

  • Haghighi, M. A., Jahandideh, A., Chamheidari, G. A., Hesaraki, S., Akbarzadeh, A. (2025). Therapeutic potential of nanofibrous scaffolds in calvarial bone regeneration. BioNanoScience, 15(3), 386.

  • Fesendouz, S. A., Hamishehkar, H., Alizadeh, E., Rahbarghazi, R., … (2025). Bactericidal activity and biofilm eradication of Pseudomonas aeruginosa by liposome-encapsulated piperacillin/tazobactam. BioNanoScience, 15(1), 87.

  • Hajati Ziabari, A., Jahandideh, A., Akbarzadeh, A., Mortazavi, P. (2025). Evaluation of the effects of curcumin/polycaprolactone nano composite on the healing of experimental osteomyelitis in rabbit tibia. Iranian Journal of Veterinary Surgery, 20(1), 38–46.

  • Hajishoreh, N. K., Mellatyar, H., Kaamyabi, S., Abasalizadeh, F., Akbarzadeh, A. (2024). Preparation and evaluation of polyurethane-based nanofibers for controlled release of simvastatin for the treatment of cardiac disorders. BioNanoScience, 14(2), 1687–1695.

Yi Yan Yang | Nanomedicine | Best Researcher Award -1584

Prof. Dr. Yi Yan Yang | Nanomedicine | Best Researcher Award

Bioprocessing Technology Institute, Singapore

👨‍🎓Profiles

🎓 Early Academic Pursuits

Yi Yan Yang began her academic journey in chemical engineering at Tsinghua University, P.R. China, where she served as an Assistant/Associate Professor from 1990 to 1998. Her foundation in polymer science and chemical engineering laid the groundwork for a remarkable career in biomedical innovation and nanomedicine. This period marked her transition into interdisciplinary research, focusing on advanced materials and their practical applications.

💼 Professional Endeavors

Her illustrious career spans multiple leadership roles within ASTAR, Singapore. She served as Group Leader at the Institute of Bioengineering and Nanotechnology (IBN), progressing to key executive positions such as Covering Executive Director at both IBN and the Institute of Bioengineering and Bioimaging. Currently, she holds the title of Distinguished Principal Scientist at the Bioprocessing Technology Institute (BTI), ASTAR. Additionally, since 2019, she has been an Adjunct Professor at the Department of Orthopedics, National University of Singapore (NUS). Her leadership and strategic vision have significantly shaped Singapore's research landscape.

📚 Contributions and Research Focus

She has made groundbreaking contributions in the fields of polymer science, nanocarriers, nanomedicine, and drug delivery systems. She has led 56 research projects, collaborating with global industry leaders like IBM, Merck MSD, and Procter & Gamble. Her work includes the development of antimicrobial and antiviral polymer coatings, polymeric hydrogels for antibody delivery, and novel nanocarriers for mRNA vaccine delivery. Her innovations extend to tackling antimicrobial resistance, polymer-based drug delivery systems, and mRNA therapeutics, significantly contributing to infectious disease treatment and next-generation vaccines.

🔭 Impact and Influence

Her research has had a global impact, as evidenced by her h-index of 95 and over 29,000 citations on Google Scholar. Recognized as a Clarivate Highly Cited Researcher in 2022, her contributions include pioneering antimicrobial polymers, which were named among Scientific American’s Top 10 World-Changing Ideas. Her technologies have led to the founding of companies like TriSafe HealthTech Pte. Ltd., translating laboratory research into real-world applications that address critical global health challenges.

🌟 Academic Publications and Patents

She has authored 303 publications in prestigious journals, including Nature Materials, Nature Nanotechnology, ACS Nano, and Advanced Materials. Her portfolio also boasts 92 patents, demonstrating her innovative spirit and commitment to advancing technology. These publications and patents underscore her expertise in drug/gene delivery systems, antimicrobial technologies, and nanomedicine.

💡 Collaborations and Partnerships

Her collaborations with globally renowned researchers, such as Dr. James L. Hedrick (IBM Almaden Research Center) and Dr. Yue Wan (Genome Institute of Singapore), have led to advancements in polymer chemistry, mRNA vaccine development, and therapeutics. Her partnerships extend to prominent institutions and industries, including Smithfield Hog Production, IHI, and ST Dynamics, fostering innovation across biomedical, pharmaceutical, and consumer care sectors.

📈 Legacy and Future Contributions

Her legacy is defined by her transformative work in biomedicine, polymer science, and infectious disease control. Her technologies have not only influenced the academic community but have also resulted in practical solutions addressing global health crises. Looking ahead, Dr. Yang remains committed to advancing mRNA nanoformulation, antimicrobial therapies, and nanocarrier systems to revolutionize healthcare delivery.

💥 Technical Skills and Expertise

She is a pioneer in the synthesis and characterization of functional polymers, lipid nanoparticles, and self-assembling macromolecules. Her expertise in nanomedicine and drug delivery is complemented by her skills in developing mRNA nanoformulations, antimicrobial polymers, and polymeric hydrogels for various biomedical applications.

👨‍🎓 Teaching Experience and Mentorship

As an Adjunct Professor at NUS, She has actively engaged in mentoring students and early-career researchers, fostering the next generation of scientists. Her leadership roles in research institutes and collaborative projects reflect her dedication to knowledge sharing and academic development.

🛠️ Consultancy and Industry Impact

Her collaborations with industry giants, including IBM, Procter & Gamble, and Merck MSD, have translated scientific innovations into commercial products. These partnerships have led to the development of groundbreaking solutions such as antimicrobial coatings, polymeric hydrogels, and nanocarriers for drug and vaccine delivery, contributing to advancements in healthcare, agriculture, and consumer care.

📖Notable Publications

  1. Durable cross-protective neutralizing antibody responses elicited by lipid nanoparticle-formulated SARS-CoV-2 mRNA vaccines
    • Authors: Bae, K.H., Shunmuganathan, B., Zhang, L., White, K.P., Yang, Y.Y.
    • Journal: npj Vaccines
    • Year: 2024
  2. A multiantigenic antibacterial nanovaccine utilizing hybrid membrane vesicles for combating Pseudomonas aeruginosa infections
    • Authors: Peng, X., Luo, Y., Yang, L., Tian, G.-B., Ding, X.
    • Journal: Journal of Extracellular Vesicles
    • Year: 2024
  3. Polymeric micellar nanoparticles for effective CRISPR/Cas9 genome editing in cancer
    • Authors: Li, Y., Li, C., Yan, J., Yang, Y.Y., Yuan, P.
    • Journal: Biomaterials
    • Year: 2024
  4. Quantitative analysis of mRNA-lipid nanoparticle stability in human plasma and serum by size-exclusion chromatography coupled with dual-angle light scattering
    • Authors: Liau, B., Zhang, L., Ang, M.J.Y., Bae, K.H., Yang, Y.Y.
    • Journal: Nanomedicine: Nanotechnology, Biology, and Medicine
    • Year: 2024
  5. Biofunctional lipid nanoparticles for precision treatment and prophylaxis of bacterial infections
    • Authors: Peng, X., Chen, J., Gan, Y., Yuan, P., Ding, X.
    • Journal: Science Advances
    • Year: 2024