Dan Chen | Nanotechnology | Best Researcher Award

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Dr. Dan Chen | Nanotechnology | Best Researcher Award

National University of Defense Technology, China

👨‍🎓Profiles

🎓 Educational Background & Career

Dr. Dan Chen is currently an Assistant Professor at the National University of Defense Technology, China. He earned his Ph.D. in Materials Science and Engineering from Huazhong University of Science and Technology, where he also completed his Bachelor’s degree. His academic journey reflects strong expertise in materials science, focused particularly on micro/nano structures, polymer microspheres, photonic crystals, and composites.

🔬 Research Focus & Contributions

Dan’s research primarily explores advanced polymer processing technologies, especially the synthesis and forming mechanisms of polymer nanospheres. He has innovated in rubbery thermoforming technology, advancing the manufacturing of precision polymer optical products with nanoscale control. His work also addresses key challenges in optical materials by developing novel non-melting forming methods that overcome orientation defects like birefringence and optical distortion, improving product precision in demanding optical applications.

🚀 Research Leadership & Projects

Dan has led multiple significant projects including:

  • A Youth Independent Innovation Fund project on non-cooled infrared detectors leveraging heterogeneous core-shell structures for enhanced upconversion luminescence.

  • A Hunan Provincial Young Researcher Fund project on high refractive index inorganic-polymer core-shell nanospheres and new elastic-state forming methods.

  • Innovation Technology and National Natural Science Foundation projects focused on thermoforming and polymer optical product manufacturing, often leading small teams of doctoral and master’s students.

🏆 Awards & Recognitions

He has been recognized with several prestigious honors such as the Fourth Batch of High-level Innovative Talents, Academic Rising Star, and China National Scholarship (a highly selective award given to 0.2% of students). He also earned the title of “Academic Nova” at Huazhong University of Science and Technology and multiple first-class scholarships throughout his studies.

⚙️ Technical Expertise & Innovations

Dan’s technical skillset spans polymer micro/nano fabrication, material modification, and precision forming technologies. He has made notable contributions to industrial applications, such as developing charge-laden masks with an efficient melt-blown process that address environmental and health challenges associated with conventional electrostatic mask filters. His interdisciplinary approach combines material science with practical product design for high-performance applications.

🌟 Impact & Future Directions

Dr. Chen’s work tackles both fundamental science and industry-relevant problems, pushing forward innovative polymer processing methods that enhance optical and functional material properties. His leadership in research projects and collaborative team management underscores his role as an emerging leader in materials science and engineering. Looking ahead, his focus on nano-engineered composites and precision polymer devices is likely to influence fields ranging from optics to biomedical materials.

📖Notable Publications

DEM-bond model: A computational framework for designing mechanically enhanced polymer nanosphere-based ordered nanostructures
Authors: Dan Chen*, §, Zhiren Chen§, Zhihong Zhu, Chucai Guo, et al.
Journal: Materials & Design
Year: 2025

Smart Window with Reversible and Instantaneous Photoluminescence based on Microsphere Structure
Authors: Dan Chen*, §, Yuang Chen§, Zhihong Zhu, Chucai Guo, et al.
Journal: ACS Applied Materials & Interfaces
Year: 2024

Spreading Behavior of Non-Spherical Particles with Reconstructed Shapes Using Discrete Element Method in Additive Manufacturing
Authors: Tengfang Zhang§, Dan Chen§, Yunming Wang*, Huamin Zhou*, et al.
Journal: Polymers
Year: 2024

Current and Future Trends for Polymer Micro/nano Processing in Industrial Applications
Authors: Dan Chen§, Yunming Wang§, Humin Zhou*, et al.
Journal: Advanced Materials
Year: 2022

Birefringence- and Optical Distortion-free Isotropic Polymer Lens Assisted by Photonic Microspheres
Authors: Dan Chen, Yunming Wang*, Yue Fu, Huamin Zhou*, et al.
Journal: ACS Applied Materials & Interfaces
Year: 2020

Yongwei Hu | Nanotechnology | Best Researcher Award

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Dr. Yongwei Hu | Nanotechnology | Best Researcher Award 

Third Affiliated Hospital of Sun Yat-sen University, China

👨‍🎓Profiles

🎓 Early Academic Pursuits

Dr. Yongwei Hu embarked on his academic journey with a strong interest in biomedical sciences and nanotechnology. From the outset, his focus gravitated toward applying advanced materials to address critical challenges in cancer therapy. His education laid a solid foundation in molecular biology, materials science, and therapeutic design, equipping him with the tools needed for interdisciplinary innovation. This early dedication led him to the prestigious Third Affiliated Hospital of Sun Yat-sen University, where he now serves as an assistant research fellow.

💼 Professional Endeavors

Currently an Assistant Research Fellow at the Third Affiliated Hospital of Sun Yat-sen University, Dr. Hu has established himself at the forefront of cancer nanomedicine research. He is actively involved in developing innovative treatment strategies for hepatocellular carcinoma (HCC), leveraging his expertise in immunotherapy and nanotechnology. His work bridges clinical medicine and biomedical engineering, ensuring translational potential from lab to patient care.

🔬 Contributions and Research Focus

Dr. Hu’s research centers on designing multifunctional nanomaterials that integrate photothermal, chemotherapeutic, and immunotherapeutic capabilities. His key contributions include:

  • Co+diABZI@J-dICG nanoparticles, which synergize photothermal therapy with metalloimmunotherapy to activate anti-tumor immunity.

  • Co+Len@OVA nanoclusters, a pH-responsive system used in combination with anti-PD1 therapy to normalize tumor vasculature and boost immune infiltration.

  • An in-situ therapy platform using electrospun fibers, targeting post-surgical HCC recurrence with localized drug delivery and immune activation.
    These innovations mark significant progress in precision oncology, where treatments are tailored for maximal efficacy and minimal systemic toxicity.

🌍 Impact and Influence

Dr. Hu’s pioneering research has significantly influenced the field of nano-enabled immunotherapy for liver cancer. By demonstrating new approaches to tumor eradication and recurrence prevention, his studies offer hope for long-term patient survival. His work has gained attention from peers in translational medicine and biomedical engineering, reinforcing his reputation as a rising leader in the integration of advanced materials with therapeutic innovation.

📈 Academic Citations and Recognition

Although early in his career, Dr. Hu’s impactful research has been recognized in academic communities through citations in high-quality journals and conference proceedings. His publications have laid foundational understanding for the therapeutic application of nanozymes, metalloimmunotherapy, and biomimetic delivery systems in hepatocellular carcinoma.

🛠️ Technical Skills

Dr. Hu is proficient in a variety of experimental techniques, including:

  • Nanoparticle synthesis and surface modification

  • Photothermal and drug release assays (in vitro and in vivo)

  • Electrospinning technology for scaffold fabrication

  • Tumor immunology assays, including flow cytometry and immunohistochemistry

  • Murine model handling and tumor microenvironment analysis

👨‍🏫 Teaching Experience

Dr. Hu has contributed to mentoring graduate students and junior researchers in the field of nanomedicine. He guides experimental design, data analysis, and manuscript preparation, fostering a new generation of interdisciplinary scientists passionate about cancer therapy innovations.

🧬 Legacy and Future Contributions

Dr. Yongwei Hu aims to continue pushing the boundaries of nanomedicine by exploring next-generation biomaterials and personalized therapeutic systems. His future research will delve deeper into tumor immune microenvironment modulation, multimodal imaging-guided therapy, and long-acting therapeutic implants for cancer recurrence prevention. His legacy is shaping up to be one of impactful innovation at the interface of materials science and oncology.

📖Notable Publications

  • Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells
    Authors: Siqi Li, Kun Li, Kang Wang, Haoyuan Yu, Xiangyang Wang, Mengchen Shi, Zhixing Liang, Zhou Yang, Yongwei Hu, Yang Li et al.
    Journal: Nature Communications
    Year: 2023

  • Self-intensified synergy of a versatile biomimetic nanozyme and doxorubicin on electrospun fibers to inhibit postsurgical tumor recurrence and metastasis
    Authors: Yongwei Hu, Yanteng Xu, Rachel L. Mintz, Xing Luo, Youqiang Fang, Yeh-Hsing Lao, Hon Fai Chan, Kai Li, Shixian Lv, Guojun Chen et al.
    Journal: Biomaterials
    Year: 2023

  • Recent advances in nanomaterials for prostate cancer detection and diagnosis
    Authors: Yongwei Hu, Shixian Lv, Jiaming Wan, Chunxiong Zheng, Dan Shao, Haixia Wang, Yu Tao, Mingqiang Li, Yun Luo
    Journal: Journal of Materials Chemistry B
    Year: 2022