Ivan Yu. Sakharov | Analytical Chemistry | Best Researcher Award

Dr. Ivan Yu. Sakharov | Analytical Chemistry | Best Researcher Award

Lomonosov Moscow State University, Russia

👨‍🎓Profiles

🏛️ Early Academic Pursuits

Ivan Yu. Sakharov began his academic journey at Lomonosov Moscow State University (LMSU), where he earned his M.Sc. in Chemical and Enzyme Kinetics in 1976. His keen interest in chemical kinetics and catalysis led him to pursue postgraduate studies, working as a senior assistant, engineer, and junior scientist at LMSU between 1976 and 1982. He was awarded a Ph.D. in Chemical Kinetics and Catalysis in 1982, setting the stage for a distinguished career in bioanalytical chemistry and biotechnology.

🏢 Professional Endeavors

Dr. Sakharov’s professional journey spans multiple prestigious institutions and international collaborations. After completing his Ph.D., he worked as a Junior Scientist at the USSR Research Cardiology Center (1982-1984). His career progressed as he became a Senior Scientist and later Head of the Protein Chemistry Division at the Laboratory of Biologically Active Substances of Hydrobionts (1984-1987). By 1992, he had earned his D.Sc. in Biotechnology, solidifying his expertise in enzyme applications. His international experience includes serving as an Associate Professor at the Industrial University of Santander, Colombia (1994-1999), and as a Full Professor at the Russian Economic Academy (2001-2011). Since 1991, he has held senior positions at LMSU, where he currently serves as Chief Scientist.

🔬 Research Focus and Innovations

Dr. Sakharov has dedicated his research to bioanalytical chemistry, with a strong focus on nucleic acid detection, chemiluminescent sensing systems, and peroxidase-catalyzed chemiluminescence. His studies in enzyme isolation and application have led to breakthroughs in medical diagnostics and bioanalytical technologies. His ongoing research has developed highly sensitive chemiluminescent assays for detecting microRNA in cancer cells, paving the way for advancements in early cancer detection and personalized medicine.

🌍 Impact and Influence

With a research career spanning over four decades, Dr. Sakharov has significantly influenced bioanalytical chemistry. His work on enzyme-based biosensors and chemiluminescent detection systems has been recognized globally. He has successfully completed 26 research projects, with one still ongoing, and has published 189 papers indexed in Scopus. His contributions have led to advancements in medical diagnostics, forensic science, and environmental monitoring.

📊 Academic Citations and Recognition

Dr. Sakharov’s research has been widely cited, with a citation index of 3,311 and an impressive h-index of 33. His influence in the scientific community is reflected in his role as a reviewer for renowned journals, including Talanta, Analytical Chemistry, Sensors & Actuators: B. Chemical, and ACS Omega. Additionally, he has authored four books with ISBN registration, further solidifying his academic presence.

🛠️ Technical Skills and Patents

Dr. Sakharov’s expertise extends beyond theoretical research; he has a robust technical background in chemiluminescence, biosensing, and enzyme kinetics. He has published 37 patents, covering innovations in bioanalytical chemistry and diagnostic technologies. His technical knowledge has enabled him to bridge the gap between research and industrial applications, leading to consultancy projects and collaborations with international research institutes.

🎓 Teaching Experience and Mentorship

As an educator, Dr. Sakharov has played a pivotal role in shaping the next generation of chemists and biotechnologists. His teaching experience includes tenure at the Industrial University of Santander, Colombia, and the Russian Economic Academy, Russia. His mentorship has guided numerous students and researchers, fostering innovation and scientific excellence.

🔗 International Collaborations and Networks

Dr. Sakharov’s research has been enriched by collaborations with esteemed institutions worldwide. He has worked closely with Guangxi Normal University (China), Chung Shan Medical University (Taiwan), Lund University (Sweden), Aarhus University (Denmark), and the University of Hawaii (USA), among others. These partnerships have facilitated cross-border advancements in bioanalytical chemistry and molecular diagnostics.

🌟 Legacy and Future Contributions

Dr. Sakharov’s legacy is built on his pioneering work in bioanalytical chemistry and enzyme-based diagnostics. His research has set new benchmarks in chemiluminescent assays and biosensing. Moving forward, his work will continue to influence medical diagnostics, biotechnology, and environmental monitoring. His ongoing projects and international collaborations ensure that his scientific contributions will have a lasting impact on research and industry.

📖Notable Publications

  • Publication: An ultrasensitive bunge bedstraw herb type DNA machine for absolute quantification of mRNA in single cell

    • Authors: C. Xu, J. Zhao, S. Chen, S. Hu, S. Zhao
    • Journal: Biosensors & Bioelectronics
    • Year: 2022
  • Publication: Comparative study of magnetic beads and microplates as supports in heterogeneous amplified assay of miRNA-141 by using mismatched catalytic hairpin assembly reaction

    • Authors: I.V. Safenkova, K.M. Burkin, O.L. Bodulev, B.B. Dzantiev, I.Y. Sakharov
    • Journal: Talanta
    • Year: 2022
  • Publication: Comparison of chemiluminescent heterogeneous and homogeneous-heterogeneous assays coupled with isothermal circular strand-displacement polymerization reaction amplification for the quantification of miRNA-141

    • Authors: A.M. Solovjev, I.I. Galkin, A.V. Medved’ko, S. Zhao, I.Y. Sakharov
    • Journal: Analyst
    • Year: 2022
  • Publication: Quantitation of MicroRNA-155 in Human Cells by Heterogeneous Enzyme-Linked Oligonucleotide Assay Coupled with Mismatched Catalytic Hairpin Assembly Reaction

    • Authors: O.L. Bodulev, I.I. Galkin, S. Zhao, O.Y. Pletjushkina, I.Y. Sakharov
    • Journal: Biosensors
    • Year: 2022
  • Publication: Modern Methods for Assessment of microRNAs

    • Authors: O.L. Bodulev, I.Y. Sakharov
    • Journal: Biochemistry (Moscow)
    • Year: 2022

Jun Dang | Analytical Chemistry | Analytical Chemistry Award

Assoc. Prof. Dr. Jun Dang | Analytical Chemistry | Analytical Chemistry Award

Northwest Institute of Plateau Biology, Chinese Academy of Sciences, China

👨‍🎓Profiles

🏫 Early Academic Pursuits

He pursued his passion for natural product chemistry and Tibetan medicine during his formative academic years. His early work focused on exploring the unique biodiversity of the Qinghai-Tibet Plateau, setting the foundation for his lifelong dedication to the chemical biology of natural products. His advanced studies led him to a role as a master’s advisor and eventually to his appointment as an associate researcher at the Northwest Institute of Plateau Biology, Chinese Academy of Sciences.

💼 Professional Endeavors

He currently serves as the Deputy Director of the Qinghai Provincial Key Laboratory of Tibetan Medicine Research. He is an active member of the Ethnic Medicine Committee of the Chinese Pharmaceutical Association and a Director of the Qinghai Pharmaceutical Association. Recognized for his contributions to natural sciences, he has been inducted into prestigious programs, including the Youth Innovation Promotion Association of the Chinese Academy of Sciences and Qinghai Province’s Kunlun Talents∙High-End Innovation and Entrepreneurship Talents Program.

🌟 Contributions and Research Focus

He specializes in the accurate discovery of functional components from the Qinghai-Tibet Plateau's unique biological resources. His innovative methods target protein agonists or inhibitors, elucidating molecular mechanisms for disease intervention. Through these pioneering studies, he bridges chemical biology with practical health applications, enriching the field with novel approaches to isolating and purifying bioactive compounds.

🌍 Impact and Influence

With 47 SCI-indexed publications and 26 granted Chinese national invention patents, Dr. Dang’s research has profoundly impacted both academia and industry. His 1150 citations, averaging 15.13 citations per article, highlight the relevance of his work. Additionally, his leadership in enterprise projects demonstrates a strong connection between scientific discovery and economic benefit, advancing pharmaceutical and biotech industries.

📚 Academic Cites and Publications

His academic contributions include 76 publications, of which 47 are SCI-indexed papers authored or co-authored as the first or corresponding author. These articles span innovative discoveries in bioactive compounds, contributing significantly to chemical biology and natural product research. He also served as the lead editor for a special issue on bioactive compounds and their molecular mechanisms against diseases.

🛠️ Technical Skills

His expertise encompasses advanced techniques in natural product chemistry, protein expression, and molecular biology. He has mastered isolating bioactive compounds and identifying their therapeutic targets, applying enzymatic, cellular, and animal model evaluations to ensure robust results.

👨‍🏫 Teaching and Mentorship

As a dedicated mentor, Dr. Dang has guided numerous master’s students, fostering the next generation of researchers in natural product chemistry and Tibetan medicine. His leadership extends beyond academia, where he collaborates with national and international researchers, amplifying the reach of his mentorship.

🎯 Legacy and Future Contributions

He envisions a future where the rich biodiversity of the Qinghai-Tibet Plateau is harnessed to solve global health challenges. By focusing on molecular mechanisms of disease intervention, he aims to create impactful, sustainable solutions in pharmaceuticals and natural medicine. His innovative methods and collaborative efforts ensure that his legacy will inspire ongoing advancements in chemical biology and natural product research.

📖Notable Publications

  1. Practically complementary size exclusion chromatography and reversed-phase liquid chromatography for the preparative separation of structurally similar flavone-C-glycosides
    • Authors: Dang, J., Lv, Y., Abd. El-Aty, A.M., Li, G.
    • Journal: Journal of Chromatography A
    • Year: 2025
  2. Isolation of highly polar galloyl glucoside tautomers from Saxifraga tangutica through preparative chromatography and assessment of their in vitro antioxidant activity
    • Authors: Tong, Y., Chu, M., Zhou, J., Abd El-Aty, A.M., Dang, J.
    • Journal: BMC Chemistry
    • Year: 2024
  3. Innovative orthogonal two-dimensional reversed-phase liquid chromatography × supercritical fluid chromatography with a phenyl/tetrazole stationary phase for the preparative isolation of diarylheptanoids
    • Authors: Dang, J., Tong, Y., Wang, Q., Li, G., Abd El-Aty, A.M.
    • Journal: Journal of Chromatography A
    • Year: 2024
  4. Protection against myocardial ischemia/reperfusion injury in mice by 3-caffeoylquinic acid isomers isolated from Saxifraga tangutica
    • Authors: Tong, Y., Li, G., Shi, X., Abd El-Aty, A.M., Dang, J.
    • Journal: RSC Advances
    • Year: 2024
  5. Impact of Preparative Isolation of C-Glycosylflavones Derived from Dianthus superbus on In Vitro Glucose Metabolism
    • Authors: Lin, Z., Zhou, X., Yuan, C., Dang, J., Li, G.
    • Journal: Molecules
    • Year: 2024
  6. An Integrated Strategy for Investigating Antioxidants from Ribes himalense Royle ex Decne and Their Potential Target Proteins
    • Authors: Liu, C., Lei, Y., Liu, Y., Dang, J., Wu, M.
    • Journal: Antioxidants
    • Year: 2023
  7. Medium- and High-Pressure Integrated Chromatographic Strategies for the Isolation and Purification of Free Radical Inhibitors from Dracocephalum heterophyllum
    • Authors: Lv, Y., Wang, Z., Wang, Q., Dang, J.
    • Journal: Separations
    • Year: 2022
  8. Preparative isolation of antioxidative furanocoumarins from Dracocephalum heterophyllum and their potential action target
    • Authors: Lv, Y., Li, C., Wang, Z., Li, G., Dang, J.
    • Journal: Journal of Separation Science
    • Year: 2022
  9. Integrated chromatographic approach for the discovery of gingerol antioxidants from Dracocephalum heterophyllum and their potential targets
    • Authors: Dang, J., Lv, Y., Li, C., Li, G., Wang, Q.
    • Journal: Analytical Methods
    • Year: 2022
  10. Ethyl Acetate Extract of Dracocephalum heterophyllum Benth Ameliorates Nonalcoholic Steatohepatitis and Fibrosis via Regulating Bile Acid Metabolism, Oxidative Stress and Inhibiting Inflammation
    • Authors: Fang, Y., Sun, D., Li, G., Wang, Q., Dang, J.
    • Journal: Separations
    • Year: 2022