Fei Zhu | Chemical Biology | Best Researcher Award

Assoc. Prof. Dr. Fei Zhu | Chemical Biology | Best Researcher Award

Xi’an Jiaotong-Liverpool University, China

👨‍🎓Profiles

🎓 Early Academic Pursuits

Assoc. Prof. Dr. Fei Zhu’s academic journey began with a strong foundation in pharmaceutical sciences and biomedical research. His early studies focused on stem cell biology, regenerative medicine, and biomaterials, laying the groundwork for his future contributions to pluripotent stem cell research and tumor immunotherapy. With a deep passion for scientific discovery, he explored innovative methodologies for cell reprogramming and tissue engineering, positioning himself as a leading expert in the field.

🏛 Professional Endeavors

Dr. Zhu is currently an Associate Professor at the Academy of Pharmacy, Xi’an Jiaotong-Liverpool University, China. His professional career is dedicated to advancing cell-based therapies and personalized medicine. He has played a pivotal role in the development of functional biomaterials that enhance cell reprogramming and organoid-based drug evaluation. His expertise extends to designing novel cancer vaccines derived from stem cell membranes, aimed at multi-cancer prevention. Through his academic and research leadership, he has fostered interdisciplinary collaborations, bridging the gap between biomedical engineering and clinical applications.

🔬 Contributions and Research Focus

Dr. Zhu’s research revolves around four key areas. His work in cell reprogramming has led to the development of highly efficient techniques using transcription factor cocktails and biomaterial-based approaches. In pluripotent stem cell-based therapy, his advancements in islet organoid development offer new possibilities for diabetes treatment. His contributions to tumor organoid-based drug evaluation have enabled the construction of patient-derived tumor organoids, allowing for precise assessments of drug efficacy, resistance, and safety.

🌍 Impact and Influence

Dr. Zhu’s research is making a significant impact in regenerative medicine and cancer therapy. His innovations in stem cell technology and biomaterials have profound implications for disease modeling, drug screening, and personalized treatment strategies. His groundbreaking publications in high-impact journals such as Nature Biomedical Engineering, Advanced Materials, and Stem Cell Reports have positioned him as a thought leader in the scientific community, influencing both academic research and potential clinical applications.

📖 Academic Citations and Recognition

Dr. Zhu’s impactful research has earned widespread recognition in leading scientific journals and international forums. His work has been cited extensively in studies related to stem cell therapy, biomaterials, and cancer immunotherapy. His insights into cell reprogramming and tumor organoids continue to shape modern biomedical sciences, contributing to the advancement of precision medicine.

🛠 Technical Skills and Expertise

Dr. Zhu possesses a diverse skill set in biomedical research, including expertise in stem cell differentiation and reprogramming, advanced biomaterial design for therapeutic applications, organoid development and drug screening, nanotechnology-based cancer immunotherapy, and high-throughput screening techniques for drug discovery. His technical expertise enables him to drive innovation in cell-based therapies and regenerative medicine.

👨‍🏫 Teaching and Mentorship

As a dedicated educator, Dr. Zhu is committed to mentoring the next generation of researchers. He actively trains students and young scientists in stem cell engineering, regenerative medicine, and tumor immunotherapy. His guidance helps students develop innovative thinking, research skills, and translational expertise, preparing them for careers in academia and industry.

🚀 Legacy and Future Contributions

Dr. Zhu’s work is paving the way for transformative advancements in medicine. His future research aims to enhance tumor organoid technology for better drug screening, develop next-generation cancer immunotherapies, improve biomaterial-based approaches for cell therapy, and translate laboratory discoveries into clinical applications for personalized medicine. With his dedication to scientific innovation, Dr. Zhu continues to push the boundaries of biomedical research, shaping the future of cell-based therapies and cancer treatment. His work holds immense promise for improving patient care and advancing global healthcare solutions.

📖Notable Publications

  • Cell-Reprogramming-Inspired Dynamically Responsive Hydrogel Boosts the Induction of Pluripotency via Phase-Separated Biomolecular Condensates

    • Authors: Fei Zhu, Nan Yan, X. Lu, J. Xu, H. Gu, J. Liang, K. Cheng, X. Wang, X. Ma, N. Ma, et al.

    • Journal: Advanced Materials

    • Year: 2024

  • Potent prophylactic cancer vaccines harnessing surface antigens shared by tumour cells and induced pluripotent stem cells

    • Authors: Nan Li, Hao Qin, Fei Zhu, Hao Ding, Yang Chen, Yixuan Lin, Ronghui Deng, Tianyu Ma, Yuanyuan Lv, Changhao Xiong, et al.

    • Journal: Nature Biomedical Engineering

    • Year: 2024

  • Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer (Preprint)

    • Authors: Bozhao Li, Feilong Qi, Fei Zhu, Zefang Lu, Meiqi Wang, Tianjiao Chu, Suying Wu, Jingyan Wei, Zhenchuan Song, Saraswati Sukumar, et al.

    • Journal: Preprint

    • Year: 2024

  • Supplementary Data from Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer (Preprint)

    • Authors: Bozhao Li, Feilong Qi, Fei Zhu, Zefang Lu, Meiqi Wang, Tianjiao Chu, Suying Wu, Jingyan Wei, Zhenchuan Song, Saraswati Sukumar, et al.

    • Journal: Preprint

    • Year: 2024

 

Huanhuan Song | Biochemistry | Best Researcher Award

Ms. Huanhuan Song | Biochemistry | Best Researcher Award

Fujian Medical University, China

👨‍🎓Profiles

🌍 Impact and Influence

Dr. Song’s research is reshaping our understanding of neuroimmune interactions. By leveraging translocator protein (TSPO)-targeted live imaging and advanced cellular models, she has revolutionized the study of microglial metabolism. Her work has broad implications, not only for MS but also for Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative conditions where lipid metabolism and neuroinflammation play critical roles. Her findings have been widely cited in immunology and neuroscience literature, reflecting their significance in the field. She has presented at international immunology conferences, contributing valuable insights into novel therapeutic strategies for neuroimmune diseases.

📚 Academic Citations and Recognition

Her research findings have gained international recognition, with citations in high-impact journals focusing on immunology, neuroscience, and lipid metabolism. She actively participates in scientific conferences and symposia, sharing her insights with the global scientific community and collaborating with fellow researchers to drive progress in neuroimmune therapeutics.

🛠️ Technical Skills

Dr. Song possesses a diverse set of technical skills, including molecular and cellular immunology, animal modeling (EAE, MS models), live imaging techniques for immune responses, flow cytometry, transcriptomic analysis, CRISPR-based gene editing, lipidomics, and metabolomics in neurodegeneration research. These skills have allowed her to conduct high-impact research that bridges fundamental science with translational applications.

🎓 Teaching and Mentorship

As part of her academic role, Dr. Song is actively involved in mentoring undergraduate and master’s students in immunological techniques and experimental neuroscience. Her guidance has helped shape young researchers, fostering innovation in the field of neuroimmunology. She is dedicated to training the next generation of scientists and encouraging interdisciplinary research approaches.

🚀 Legacy and Future Contributions

Dr. Song is committed to advancing precision medicine in neuroinflammation, with future work aimed at developing novel drug interventions targeting lipid metabolism pathways. By translating fundamental research into clinical applications, she envisions creating more effective and personalized treatments for patients suffering from MS and other chronic neuroinflammatory conditions. Her pioneering research on CYP7B1 is set to leave a lasting impact on immunotherapy and neuropharmacology, making her a trailblazer in the intersection of lipid metabolism and neuroimmune regulation. With her continued contributions, Dr. Song is shaping the future of neuroinflammation research and therapeutic development.

📖Notable Publications

CYP7B1 Deficiency Impairs Myeloid Cell Activation in Autoimmune Disease of the Central Nervous System
Authors: Huanhuan Song, Aowei Lv, Zhibao Zhu, Runyun Li, Qiuping Zhao, Xintong Yu, Junyi Jiang, Xiang Lin, Cunjin Zhang, Rui Li, et al.
Journal: PNAS Nexus
Year: 2024

Tanshinone IIA Alleviates Brain Damage in a Mouse Model of Neuromyelitis Optica Spectrum Disorder by Inducing Neutrophil Apoptosis
Authors: Ye Gong, Ya-ling Zhang, Zhen Wang, Huanhuan Song, Yuan-chu Liu, Aowei Lv, Li-li Tian, Wen-li Zhu, Ying Fu, Xiao-li Ding, et al.
Journal: Journal of Neuroinflammation
Year: 2020