Fei Zhu | Chemical Biology | Best Researcher Award

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Assoc. Prof. Dr. Fei Zhu | Chemical Biology | Best Researcher Award

Xi’an Jiaotong-Liverpool University, China

👨‍🎓Profiles

🎓 Early Academic Pursuits

Assoc. Prof. Dr. Fei Zhu’s academic journey began with a strong foundation in pharmaceutical sciences and biomedical research. His early studies focused on stem cell biology, regenerative medicine, and biomaterials, laying the groundwork for his future contributions to pluripotent stem cell research and tumor immunotherapy. With a deep passion for scientific discovery, he explored innovative methodologies for cell reprogramming and tissue engineering, positioning himself as a leading expert in the field.

🏛 Professional Endeavors

Dr. Zhu is currently an Associate Professor at the Academy of Pharmacy, Xi’an Jiaotong-Liverpool University, China. His professional career is dedicated to advancing cell-based therapies and personalized medicine. He has played a pivotal role in the development of functional biomaterials that enhance cell reprogramming and organoid-based drug evaluation. His expertise extends to designing novel cancer vaccines derived from stem cell membranes, aimed at multi-cancer prevention. Through his academic and research leadership, he has fostered interdisciplinary collaborations, bridging the gap between biomedical engineering and clinical applications.

🔬 Contributions and Research Focus

Dr. Zhu’s research revolves around four key areas. His work in cell reprogramming has led to the development of highly efficient techniques using transcription factor cocktails and biomaterial-based approaches. In pluripotent stem cell-based therapy, his advancements in islet organoid development offer new possibilities for diabetes treatment. His contributions to tumor organoid-based drug evaluation have enabled the construction of patient-derived tumor organoids, allowing for precise assessments of drug efficacy, resistance, and safety.

🌍 Impact and Influence

Dr. Zhu’s research is making a significant impact in regenerative medicine and cancer therapy. His innovations in stem cell technology and biomaterials have profound implications for disease modeling, drug screening, and personalized treatment strategies. His groundbreaking publications in high-impact journals such as Nature Biomedical Engineering, Advanced Materials, and Stem Cell Reports have positioned him as a thought leader in the scientific community, influencing both academic research and potential clinical applications.

📖 Academic Citations and Recognition

Dr. Zhu’s impactful research has earned widespread recognition in leading scientific journals and international forums. His work has been cited extensively in studies related to stem cell therapy, biomaterials, and cancer immunotherapy. His insights into cell reprogramming and tumor organoids continue to shape modern biomedical sciences, contributing to the advancement of precision medicine.

🛠 Technical Skills and Expertise

Dr. Zhu possesses a diverse skill set in biomedical research, including expertise in stem cell differentiation and reprogramming, advanced biomaterial design for therapeutic applications, organoid development and drug screening, nanotechnology-based cancer immunotherapy, and high-throughput screening techniques for drug discovery. His technical expertise enables him to drive innovation in cell-based therapies and regenerative medicine.

👨‍🏫 Teaching and Mentorship

As a dedicated educator, Dr. Zhu is committed to mentoring the next generation of researchers. He actively trains students and young scientists in stem cell engineering, regenerative medicine, and tumor immunotherapy. His guidance helps students develop innovative thinking, research skills, and translational expertise, preparing them for careers in academia and industry.

🚀 Legacy and Future Contributions

Dr. Zhu’s work is paving the way for transformative advancements in medicine. His future research aims to enhance tumor organoid technology for better drug screening, develop next-generation cancer immunotherapies, improve biomaterial-based approaches for cell therapy, and translate laboratory discoveries into clinical applications for personalized medicine. With his dedication to scientific innovation, Dr. Zhu continues to push the boundaries of biomedical research, shaping the future of cell-based therapies and cancer treatment. His work holds immense promise for improving patient care and advancing global healthcare solutions.

📖Notable Publications

  • Cell-Reprogramming-Inspired Dynamically Responsive Hydrogel Boosts the Induction of Pluripotency via Phase-Separated Biomolecular Condensates

    • Authors: Fei Zhu, Nan Yan, X. Lu, J. Xu, H. Gu, J. Liang, K. Cheng, X. Wang, X. Ma, N. Ma, et al.

    • Journal: Advanced Materials

    • Year: 2024

  • Potent prophylactic cancer vaccines harnessing surface antigens shared by tumour cells and induced pluripotent stem cells

    • Authors: Nan Li, Hao Qin, Fei Zhu, Hao Ding, Yang Chen, Yixuan Lin, Ronghui Deng, Tianyu Ma, Yuanyuan Lv, Changhao Xiong, et al.

    • Journal: Nature Biomedical Engineering

    • Year: 2024

  • Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer (Preprint)

    • Authors: Bozhao Li, Feilong Qi, Fei Zhu, Zefang Lu, Meiqi Wang, Tianjiao Chu, Suying Wu, Jingyan Wei, Zhenchuan Song, Saraswati Sukumar, et al.

    • Journal: Preprint

    • Year: 2024

  • Supplementary Data from Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer (Preprint)

    • Authors: Bozhao Li, Feilong Qi, Fei Zhu, Zefang Lu, Meiqi Wang, Tianjiao Chu, Suying Wu, Jingyan Wei, Zhenchuan Song, Saraswati Sukumar, et al.

    • Journal: Preprint

    • Year: 2024

 

Ghanshyam Teli | Medicinal Chemistry | Best Researcher Award

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Mr. Ghanshyam Teli | Medicinal Chemistry | Best Researcher Award

School of Pharmacy, Sangam University, India

👨‍🎓Profiles

👨‍🎓 Early Academic Pursuits

Mr. Ghanshyam Teli’s academic journey began with a strong foundation in pharmacy. He earned his B. Pharmacy from Geetanjali University in 2019 with a commendable 73.7%. His academic pursuit continued with a M. Pharmacy from ISF College of Pharmacy in 2021, where he achieved an impressive 82%. Currently, he is pursuing his Ph.D. at Baba Farid University of Health Sciences, enhancing his expertise in the field. His early academic focus was on chemical synthesis and drug discovery, where he worked on several research projects related to anti-cancer agents and inhibitors of oncogenic pathways.

🧑‍🔬 Professional Endeavors

Mr. Teli has gained considerable professional experience, particularly in both academic and industrial settings. He has worked for 1.5 years as an Assistant Professor at the School of Pharmacy, Sangam University, Bhilwara, India, where he has been able to share his knowledge with students while continuing his research. His professional experience also includes 13 months at United Biotech Pvt Ltd as an Assistant R&D Chemist, where he contributed to several high-impact projects, including the synthesis of 4-Thiazolidinone derivatives and the development of Paclitaxel-HSA complex. Additionally, he spent 1 year as a Junior Research Fellow (JRF) at Acharya and B.M. Reddy College of Pharmacy in Bengaluru, further strengthening his research expertise.

🔬 Contributions and Research Focus

Mr. Teli's research contributions have primarily focused on drug design, synthesis, and evaluation, with a particular emphasis on creating compounds for anti-cancer treatment. His work on 4-thiazolidinone conjugates as potential anti-breast cancer agents is notable, along with his project on the discovery of triangular heterocyclic molecules to inhibit dual oncogenic pathways. His research aims to contribute to developing novel therapeutic strategies for cancer treatment, especially targeting HSP90 and BRAF kinases.

🌍 Impact and Influence

Mr. Teli's professional journey demonstrates his commitment to both academia and industry. His industrial experience has allowed him to engage in multi-step synthesis processes and biological evaluations, making a tangible impact on pharmaceutical development. As an educator, he strives to impart his knowledge and inspire the next generation of pharmacists, sharing insights from both his research and industry experience. His contributions aim to foster innovations in drug design and therapy, particularly in cancer treatments.

📚 Academic Cites and Recognition

While Mr. Teli’s academic work is still evolving, his research projects on drug discovery, particularly in the field of cancer, have the potential for future recognition and citations. His detailed work in the design and synthesis of bioactive compounds, particularly those related to anti-cancer and anti-breast cancer agents, is likely to gain traction and be cited by peers in the academic and research communities.

💻 Technical Skills

Mr. Teli is proficient in several technical aspects of pharmaceutical chemistry, including: Synthesis of chemical compounds and characterization through advanced spectroscopy techniques such as UV, IR, and 1H NMR. Docking studies and predicting ADMET properties (Absorption, Distribution, Metabolism, Excretion, and Toxicity) for potential drug candidates. Handling specialized equipment such as Flash Chromatography, Column Chromatography, Rota-evaporator, Vacuum dryer, UV-Vis Spectrophotometer, and pH meter. Expertise in computational tools like ChemDraw, Autodock, Molegro Virtual Docker (MVD), Pymol, and Discovery Studio, which aid in the structure-activity relationship (SAR) analysis and molecular modeling.

👩‍🏫 Teaching Experience

As an Assistant Professor at the School of Pharmacy, Sangam University, Mr. Teli has honed his teaching skills, fostering a rich learning environment. His ability to explain complex concepts in pharmacy and drug design to students reflects his deep knowledge and communication skills. His teaching approach emphasizes practical application and encourages critical thinking. By sharing his industrial and research experiences, he connects students with real-world pharmaceutical challenges, aiming to inspire future innovations.

🌱 Legacy and Future Contributions

Mr. Teli’s ongoing research and academic efforts hold significant promise for the future of pharmacy education and drug discovery. His work on the synthesis of novel anti-cancer agents, especially those targeting key oncogenic pathways, has the potential to drive breakthroughs in cancer therapy. As he continues to pursue his Ph.D., Mr. Teli is committed to growing as a researcher and educator. He seeks to expand his knowledge, hone his technical skills, and make valuable contributions to drug development while guiding the next generation of pharmaceutical professionals.

📖Notable Publications

  • Synthetic product-based approach toward potential antileishmanial drug development
  • Authors: Pal, R., Teli, G., Akhtar, M.J., Matada, G.S.P.
    Journal: European Journal of Medicinal Chemistry
    Year: 2024
  • An outlook of docking analysis and structure-activity relationship of pyrimidine-based analogues as EGFR inhibitors against non-small cell lung cancer (NSCLC)
  • Authors: Pal, R., Teli, G., Sengupta, S., Maji, L., Purawarga Matada, G.S.
    Journal: Journal of Biomolecular Structure and Dynamics
    Year: 2024
  • Explanatory review on pyrimidine/fused pyrimidine derivatives as anticancer agents targeting Src kinase
  • Authors: Teli, G., Pal, R., Maji, L., Purawarga Matada, G.S., Sengupta, S.
    Journal: Journal of Biomolecular Structure and Dynamics
    Year: 2024
  • Designing strategies, structural activity relationship and biological activity of recently developed nitrogen containing heterocyclic compounds as epidermal growth factor receptor tyrosinase inhibitors
  • Authors: Pal, R., Teli, G., Matada, G.S.P., Dhiwar, P.S.
    Journal: Journal of Molecular Structure
    Year: 2023
  • The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasis
  • Authors: Pal, R., Teli, G., Akhtar, M.J., Matada, G.S.P.
    Journal: European Journal of Medicinal Chemistry
    Year: 2023