Kwang Hoe Kim | Analytical Chemistry | Best Researcher Award

Dr. Kwang Hoe Kim | Analytical Chemistry | Best Researcher Award

Cellkey Inc, South Korea

👨‍🎓Profile

🎓 Early Academic Pursuits

Dr. Kwang Hoe Kim’s academic journey began at Chungnam National University, South Korea, where he completed his Bachelor’s degree in Chemistry in March 2009. This foundational training in the sciences paved the way for his later research. In 2010, he advanced to the Graduate School of Analytical Science and Technology at the same institution, earning a Master’s degree (M.S.) in February 2012. Under the guidance of Professor Jong Shin Yoo, he developed key skills in mass spectrometry and glycoproteomics. He continued to build on this expertise, earning his Ph.D. in 2019, further honing his skills in mass spectrometry and biomarker discovery.

🧪 Professional Endeavors

Dr. Kim’s professional journey has been marked by his leadership in advancing the field of bioanalytical research, particularly in oncology. In January 2021, he took on the role of Head of the Bio R&D Center at CellKey, where he focuses on the development of diagnostic biomarkers for cancer detection and management. His work also includes advancing companion diagnostics in immuno-oncology, leveraging mass spectrometry for clinical applications. Prior to this, he worked as a Postdoctoral Researcher at the Korea Basic Science Institute, where he made significant contributions to the detection of hepatocellular carcinoma, a leading form of liver cancer.

🔬 Contributions and Research Focus

Dr. Kim’s research has been deeply focused on the application of mass spectrometry for cancer diagnosis and biomarker discovery. His work includes developing liquid chromatography-mass spectrometry-based methods to identify cancer-associated proteins and glycoproteins. At the Research Center for Bioconvergence Analysis, he worked on developing a multi-biomarker panel for hepatocellular carcinoma detection, using mass spectrometry to enhance diagnostic sensitivity. His work in optimizing immunoprecipitation/targeted mass spectrometry methods has made significant contributions to the analytical sensitivity of peptide and glycopeptide analyses.

🌍 Impact and Influence

Dr. Kim’s work has had a notable impact on both the scientific community and clinical applications. His research into mass spectrometry-based diagnostic methods has helped pave the way for more accurate and sensitive detection of cancer biomarkers, particularly in liver cancer. His development of multi-biomarker panels for cancer detection is a key step forward in precision medicine, which promises to enhance personalized treatment strategies for cancer patients. The clinical applications of his research in immuno-oncology also offer promise in the future of cancer care.

📚 Academic Citations

Dr. Kim’s research has earned recognition in the scientific community, with several published papers and citations highlighting his contributions to mass spectrometry and cancer biomarker research. His work on aberrant glycoproteins in colorectal cancer and hepatocellular carcinoma has been instrumental in advancing the understanding of cancer biomarkers, leading to increased citations in the fields of oncology and analytical chemistry.

🛠️ Technical Skills

Dr. Kim possesses a wide range of technical skills, particularly in the area of mass spectrometry. He is an expert in developing and applying various mass spectrometry techniques such as multiple reaction monitoring (MRM), parallel reaction monitoring (PRM), and high-resolution mass spectrometry using MALDI MS and FT-ICR. Additionally, he has extensive experience in protein quantification through immunoprecipitation and targeted mass spectrometry, particularly for low-abundance proteins. His technical expertise extends to the development of methods for high-throughput peptide and glycopeptide analysis.

👨‍🏫 Teaching Experience

Throughout his career, Dr. Kim has been actively involved in mentoring and educating the next generation of scientists. While pursuing his graduate studies, he worked as a research assistant and fellow, helping to guide students in laboratory techniques and research methodologies. His role as a leader in the Bio R&D Center at CellKey also involves sharing his expertise with younger researchers and fostering a collaborative environment for innovation in cancer diagnostics.

🌱 Legacy and Future Contributions

Looking to the future, Dr. Kim’s work promises to leave a lasting legacy in the fields of mass spectrometry and cancer diagnostics. His continued efforts to refine diagnostic biomarkers and improve detection methods are expected to contribute significantly to the fields of personalized medicine and immuno-oncology. As he expands his research into new areas, his contributions will likely inspire new diagnostic tools and clinical applications, shaping the future of cancer research and treatment.

🔮 Future Goals

Dr. Kim’s future goals include the further development of advanced diagnostics for early cancer detection and the continuous improvement of biomarker panels. With the evolving field of immuno-oncology, he plans to work on improving companion diagnostics, focusing on the use of mass spectrometry to assess tumor microenvironments and treatment responses. His dedication to advancing the science of cancer biomarkers positions him at the forefront of precision medicine, with the potential to greatly impact clinical practices.

📖Notable Publications

LC-MS/MS-Based Site-Specific N-Glycosylation Analysis of VEGFR-IgG Fusion Protein for Sialylation Assessment Across IEF Fractions
  • Authors: Kim, K. H., Ji, E. S., Lee, J. Y., Song, J. H., & Ahn, Y. H.
    Journal: Molecules
    Year: 2024
Measuring fucosylated alpha‐fetoprotein in hepatocellular carcinoma: A comparison of μTAS and parallel reaction monitoring
  • Authors: Kim, K. H., Lee, S. Y., Baek, J. H., Lee, S. Y., Kim, J. Y., & Yoo, J. S.
    Journal: PROTEOMICS–Clinical Applications
    Year: 2021
Absolute Quantification of N-Glycosylation of Alpha-Fetoprotein Using Parallel Reaction Monitoring with Stable Isotope-Labeled N-Glycopeptide as an Internal Standard
  • Authors: Kim, K. H., Lee, S. Y., Kim, D. G., Lee, S. Y., Kim, J. Y., & Yoo, J. S.
    Journal: Analytical Chemistry
    Year: 2020
BMDMSNP: A comprehensive ESI-MS/MS spectral library of natural compounds
  • Authors: Lee, S., Hwang, S., Seo, M., Shin, K. B., Kim, K. H., Park, G. W., & No, K. T.
    Journal: Phytochemistry
    Year: 2020
Mass spectrometry analysis of glycoprotein biomarkers in human blood of hepatocellular carcinoma
  • Authors: Kim, K. H., Kim, J. Y., & Yoo, J. S.
    Journal: Expert Review of Proteomics
    Year: 2019
Parallel reaction monitoring with multiplex immunoprecipitation of N-glycoproteins in human serum for detection of hepatocellular carcinoma
  • Authors: Kim, K. H., Park, G. W., Jeong, J. E., Ji, E. S., An, H. J., Kim, J. Y., & Yoo, J. S.
    Journal: Analytical and Bioanalytical Chemistry
    Year: 2019

Martín Fernández Baldo | Bioanalítica | Best Researcher Award

Dr. Martín Fernández Baldo | Bioanalítica | Best Researcher Award 

Universidad Nacional de San Luis, Argentina

👨‍🎓 Profile

🎓 Early Academic Pursuits

He pursued a solid academic journey, beginning with his primary education at Justo José de Urquiza in Maipú, Mendoza, where he graduated in December 1989. He later attended Liceo Militar General Espejo for his secondary education, graduating as a Bachiller and Subteniente de Reserva del Arma de Infantería in December 1994.

🏛 Higher Education

Fernández Baldo pursued his Bachelor's degree in Biochemistry from the Universidad Nacional de San Luis, completing his studies in 2007. He later obtained his Doctorate in Biochemistry, with his thesis titled "Control Biológico en Postcosecha: Desarrollo de Metodologías para la Detección y Cuantificación de Mohos Fitopatógenos y Micotoxinas". His thesis work was guided by Dr. María Isabel Sanz Ferramola (Director) and Dr. Germán Messina (Co-Director).

💼 Professional Endeavors

Currently, Martín Fernández Baldo is based in San Luis, Argentina, where he works at the Universidad Nacional de San Luis. He holds positions in both the Facultad de Química, Bioquímica y Farmacia in the Department of Chemistry and the Department of Bioquímica y Ciencias Biológicas. He is associated with CONICET and works in the Instituto de Química de San Luis (INQUISAL), contributing to the Laboratorio de Bioanalítica.

🔬 Contributions and Research Focus

Fernández Baldo's research is centered around bioanalytical chemistry and nanotechnology. He has expertise in synthesizing nanomaterials using both chemical and biological methods (such as microorganisms like fungi and bacteria). His work includes the use of these nanomaterials in biosensors with electrochemical detection or laser-induced fluorescence (LIF) for the determination of various biochemical, environmental, and agro-food analytes.

In recent years, his research has expanded to focus on the early diagnosis of epithelial cancers (breast, colorectal, lung, prostate) through the determination of specific tumor markers. He is also dedicated to the diagnosis of infectious diseases like parasitic, viral, and fungal infections.

🌍 Impact and Influence

Fernández Baldo's work in the field of bioanalytical chemistry and nanotechnology is making significant strides in improving diagnostic tools for both cancer and infectious diseases. His interdisciplinary approach, combining nanotechnology with bioanalytical methods, has had a notable impact on public health diagnostics, especially in low-resource settings where early and accurate detection is critical.

🛠️ Technical Skills

His technical expertise spans a variety of advanced techniques, including: Nanomaterial synthesis (chemical and biological methods). Characterization of nanomaterials using: UV-vis, XRD, XRF, FTIR, DLS, SEM, EDS, TEM. Biosensor development for: Electrochemical detection, Laser-induced fluorescence (LIF) detection.

🏅 Teaching Experience

Throughout his career, Martín Fernández Baldo has also been involved in teaching and mentorship. He contributes to postgraduate courses, such as the course on "Instrumental Analysis Methods: Biological Applications", offered by the Universidad Nacional de Cuyo. His participation in academia extends to supervising students and guiding research projects in the fields of analytical chemistry and bioanalysis.

📚 Legacy and Future Contributions

Looking forward, Martín Fernández Baldo aims to further his research in bioanalytical chemistry and nanotechnology, specifically focusing on the early diagnosis of cancers and infectious diseases. His goal is to develop more efficient, cost-effective diagnostic tools that can be applied globally. His work will likely continue to influence the fields of public health, analytical chemistry, and nanotechnology, contributing to the betterment of global diagnostic practices.

📖  Notable Publications

Copper nanoparticles as a potential emerging pollutant: Divergent effects in the agriculture, risk-benefit balance and integrated strategies for its use

Authors: Tortella, G., Rubilar, O., Fincheira, P., Fernandez-Baldo, M., Seabra, A.B.
Journal: Emerging Contaminants
Year: 2024

Metal nanoparticles and pesticides under global climate change: Assessing the combined effects of multiple abiotic stressors on soil microbial ecosystems

Authors: Fernández-Triana, I., Rubilar, O., Parada, J., Seabra, A.B., Tortella, G.R.
Journal: Science of the Total Environment
Year: 2024

Electrochemical microfluidic immunosensor with graphene-decorated gold nanoporous for T-2 mycotoxin detection

Authors: Fernandez Solis, L.N., Silva Junior, G.J., Bertotti, M., Fernández-Baldo, M.A., Regiart, M.
Journal: Talanta
Year: 2024

Advances in Nanomaterials and Composites Based on Mesoporous Materials as Antimicrobial Agents: Relevant Applications in Human Health

Authors: Gomez, G.E., Hamer, M., Regiart, M.D., Soler Illia, G.J.A.A., Fernández-Baldo, M.A.
Journal: Antibiotics
Year: 2024

Use of Mechanochemical Methodology to Explore the Formation of a New Crystalline Phase in the Curcumin-Quercetin System

Authors: D'Vries, R.F., Pastrana-Dávila, A., Pantoja, K.D., Gomez, G.E., Fernández-Baldo, M.A.
Journal: ChemistrySelect
Year: 2024

Five years of advances in electrochemical analysis of protein biomarkers in lung cancer: a systematic review

Authors: Regiart, M., Fernández-Baldo, M.A., Navarrete, B.A., Valero, T., Ortega, F.G.
Journal: Frontiers in Chemistry
Year: 2024

Origami Paper-Based Electrochemical Immunosensor with Carbon Nanohorns-Decorated Nanoporous Gold for Zearalenone Detection

Authors: Laza, A., Pereira, S.V., Messina, G.A., Regiart, M.D., Bertolino, F.A.
Journal: Chemosensors
Year: 2024