Yuejai Kang | Medicinal Chemistry | Best Researcher Award

Assist. Prof. Dr. Yuejai Kang | Medicinal Chemistry | Best Researcher Award

Kunsan National University, South Korea

Profiles

Early Academic Pursuits

Dr. Yuejai Kang began his academic journey with a background in social sciences, equipping him with a broad perspective that complements his scientific approach. Driven by a passion for marine and aquatic ecosystems, he transitioned into the field of Aquatic Life Medicine, completing both undergraduate and postgraduate studies. His academic pursuits culminated in a doctoral degree in Biotechnology, with a specialization in aquatic animal diseases. His Ph.D. research focused on enhancing disease resistance in olive flounder (Paralichthys olivaceus) through systems producing CpG DNA and double-stranded RNA, forming the basis for his long-term research in aquatic immunology and disease prevention.

Professional Endeavors

As an Assistant Professor in the Department of Aquatic Life Medicine at Kunsan National University, Dr. Kang has built a career spanning over two decades in aquatic veterinary sciences. His professional responsibilities encompass research leadership, academic instruction, and mentorship, alongside active participation in interdisciplinary projects addressing aquatic animal health. He continues to collaborate with government and industry partners, applying academic insights to real-world aquaculture challenges.

Contributions and Research Focus

Dr. Kang’s research is primarily centered on understanding and managing viral and bacterial diseases in aquatic animals. He has contributed significantly to the development of vaccines, immunostimulants, therapeutics, and antibiotics tailored for use in aquaculture. His work explores host-pathogen interactions, mechanisms of disease resistance, and the molecular basis of immunity in fish species. He has investigated the antiviral potential of agents such as remdesivir against fish viruses belonging to the Rhabdoviridae family. Additionally, he is extending his expertise into the study of environmental toxicology, examining how pollutants and environmental stressors affect aquatic disease dynamics.

Impact and Influence

Dr. Kang’s work has had a tangible impact on the aquaculture sector, improving disease control strategies and promoting sustainable fish farming practices. His studies have helped enhance disease resistance in cultured species, reducing mortality and economic losses in aquaculture operations. His scientific contributions are influencing policy development and management practices in aquatic health both nationally and internationally.

Academic Citations and Publications

With a strong publication record, Dr. Kang has authored 50 research papers in peer-reviewed journals, contributing to the global knowledge base in aquatic health science. His work is frequently cited by peers in related fields such as virology, marine biology, fish pathology, and biotechnology, underlining the broad relevance and scientific merit of his research. Notably, his publication on the antiviral effects of remdesivir has gained recognition for its innovative approach to controlling viral infections in aquatic species.

Technical Skills

Dr. Kang’s technical expertise includes advanced molecular biology methods, such as nucleic acid-based vaccine development, diagnostic PCR, and immunological assays. He is adept in laboratory and field-based pathogen challenge experiments, cell culture, and microbiological diagnostics. His hands-on proficiency supports high-quality experimental design and data interpretation in fish health research.

Teaching Experience

In addition to his research, Dr. Kang plays a vital role in academic instruction and student development. He teaches core courses in aquatic medicine and biotechnology and has supervised numerous undergraduate and postgraduate research projects. He emphasizes practical learning, scientific reasoning, and innovation, inspiring students to pursue careers in marine and aquatic science.

Legacy and Future Contributions

Looking ahead, Dr. Kang aims to further explore the intersection of environmental toxicology and aquatic disease, with a focus on how emerging contaminants affect fish health and immune responses. He is committed to advancing integrated disease management approaches and fostering collaborative research networks. Through his continued efforts, he seeks to contribute to the sustainability and resilience of aquaculture systems worldwide.

Notable Publications

First report and pathogenicity of Vibrio campbellii (VC<sub>AHPND</sub>) isolated in South Korea
Authors: Choi H.-J., Choi D.-Y., Lee J.-H., Kim J.-H., Kang Y.J.
Journal: Journal of Fish Diseases
Year: 2024

Process optimization for microfluidic preparation of liposomes using food-grade components
Authors: Hong S.-C., Hong C.R., Kim M., Kang Y.J., Jung Y.H., Park K.-M., Choi J., Chang P.-S.
Journal: Food Chemistry
Year: 2024

Protective Effects of Long Double-Stranded RNA with Different CpG Motifs against Miamiensis avidus and Viral Hemorrhagic Septicemia Virus (VHSV) Infections in Olive Flounder (Paralichthys olivaceus)
Authors: Choi H.-J., Choi D.-Y., Park J.-J., Jung H.J., Kim B.-S., Hong S.-C., Kim J.-H., Kang Y.J.
Journal: Fishes
Year: 2024

The use, application and efficacy of biofloc technology (BFT) in shrimp aquaculture industry: A review
Authors: Yu Y.-B., Choi J.-H., Lee J.-H., Jo A.-H., Lee J.-W., Choi H.J., Kang Y.J., Choi C.Y., Kang J.-C., Lee K.M., et al.
Journal: Environmental Technology and Innovation
Year: 2024

Toxic Effects of Microplastics (Polyethylene) Exposure on Neurotransmitter, Stress Indicators and Immunity in Korean Bullhead (Pseudobagrus fulvidraco)
Authors: Lee J.-H., Choi J.-H., Kang Y.J., Choi Y.J., Choi C.Y., Kang J.-C., Kim J.-H.
Journal: SSRN
Year: 2024

Zhao Wei | Medicinal Chemistry | Best Researcher Award

Assoc. Prof. Dr. Zhao Wei | Medicinal Chemistry | Best Researcher Award

Air Force Medical University, China

Profiles

Early Academic Pursuits

Dr. Zhao Wei began his academic journey in chemistry, completing undergraduate studies at Nankai University, where he was recognized for academic excellence. He pursued doctoral studies in Medicinal Chemistry at the Academy of Military Medical Sciences under the mentorship of esteemed academician Li Song. His doctoral work laid a strong foundation for his future contributions in the field of drug design and medicinal chemistry.

Professional Endeavors

After completing his doctoral studies, Dr. Zhao commenced his professional academic career at the School of Pharmacy, Air Force Medical University. He joined the institution as a lecturer and has since advanced to the role of Associate Professor. Throughout his tenure, he has actively engaged in both undergraduate and postgraduate teaching, while simultaneously driving research efforts in drug discovery, particularly targeting neurological disorders.

Contributions and Research Focus

Dr. Zhao has made significant strides in the design, synthesis, and screening of small-molecule therapeutics. His core research areas include acetylcholinesterase (AChE) reactivators aimed at treating organophosphorus poisoning through novel non-quaternary reactivators with dual-site binding capabilities. Over 300 compounds have been synthesized, with more than 30 demonstrating in vitro reactivation potency and 2 showing promising in vivo efficacy. In the development of anti-Alzheimer’s agents, he synthesized over 100 quinoline-based AChE inhibitors, more than 20 of which showed potent enzyme inhibition. Some compounds demonstrated dual AChE/BChE activity, giving rise to the concept of Fragment-Informed Structure-Activity Relationship (SAR). In neuroprotective agent development, he synthesized over 100 dihydropyridine derivatives targeting ASICs and GPR30, identifying five highly active compounds with significant in vitro neuroprotective effects.

Impact and Influence

Dr. Zhao’s work addresses pressing global health challenges, such as neurodegenerative diseases and chemical poisoning. His innovative strategies for drug reactivation and multi-target inhibition have introduced new directions in medicinal chemistry. His success in translating fragment-based insights into potent therapeutic candidates highlights his influence in shaping modern drug design methodologies.

Academic Cites and Recognition

Dr. Zhao’s scholarly output has garnered attention in high-impact medicinal chemistry and pharmacology journals. His research papers are widely cited by academic peers, reflecting the importance and applicability of his findings across both theoretical and applied medicinal sciences.

Technical Skills and Methodological Strengths

He possesses deep expertise in organic synthesis, bioassays for neuropharmacological evaluation, and structure-based drug design. His ongoing work incorporates Fragment-Based Drug Design (FBDD), molecular docking, and SAR analysis, ensuring an integrative approach to rational drug development.

Teaching Experience and Mentorship

As a faculty member of the School of Pharmacy, Dr. Zhao has been instrumental in developing curriculum content for medicinal chemistry courses. He has supervised numerous undergraduate and graduate research projects, instilling analytical and experimental skills in the next generation of pharmaceutical scientists.

Professional Leadership

He serves as Vice Chairperson of the Pharmaceutical Chemistry Professional Committee under the Shaanxi Pharmaceutical Society, contributing to academic exchange, policy development, and advancement of pharmaceutical research within the region.

Legacy and Future Contributions

Dr. Zhao Wei continues to expand his research into innovative therapeutic strategies for nervous system disorders. His long-term vision includes the development of multifunctional drug candidates that integrate efficacy, safety, and novel mechanisms of action. With a commitment to excellence in both education and research, he is poised to leave a lasting legacy in the field of medicinal chemistry.

Notable Publications

Screening of efficient salicylaldoxime reactivators for DFP and paraoxon-inhibited acetylcholinesterase
Authors: Zhao Wei, Dongxu Zhang, Xueying Liu, Huifang Nie, Qin Ouyang, Xinlei Zhang, Zhibing Zheng
Journal: RSC Medicinal Chemistry
Year: 2024

Lifestyle habits and gastric cancer in an East Asian population: a Mendelian randomization study
Authors: Yuegui Tan, Zhao Wei, Kun Liu, Yuzhen Qin, Wenqi Hui, Zhao Wei
Journal: Frontiers in Oncology
Year: 2023

Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice
Authors: Zhao Wei, Xinlei Zhang, Huifang Nie, Lin Yao, Yanqin Liu, Zhibing Zheng, Qin Ouyang
Journal: Molecules
Year: 2022

Drug Synthesis and Analysis of an Acetylcholinesterase Inhibitor: A Comprehensive Medicinal Chemistry Experience for Undergraduates
Authors: Yang J., Yuan Y., Gu J., Li A., Wei Z., Ouyang Q.
Journal: Journal of Chemical Education
Year: 2021